Date published: 2025-11-1

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β-defensin 44 Inhibitors

β-defensin 44 Inhibitors encompass a diverse group of chemicals that are conjectured to modulate the activity of β-defensin 44, a protein encoded by the β-defensin 44 gene, through indirect means. These inhibitors do not directly interact with the protein but rather influence the cellular and physiological pathways that regulate its expression and function. The assumed mechanisms of action are varied, underlying the complexity and multifaceted nature of protein modulation.

Key representatives in this class include compounds like Vitamin D3 and Zinc Sulfate, known for their roles in skin health and immune function, which are crucial for the optimal functioning of β-defensin 44. Similarly, Retinoic Acid and Eicosapentaenoic Acid (EPA) are included based on their potential to influence skin cell differentiation and inflammatory responses, respectively. The inclusion of natural extracts like Green Tea Extract and Lactoferrin reflects the growing interest in the use of nutraceuticals for modulating immune and skin health. Curcumin and Quercetin, known for their anti-inflammatory properties, are thought to influence β-defensin 44 through pathways like NF-kB and oxidative stress regulation.

Furthermore, Resveratrol, Glucosamine, Selenium, and Vitamin C are included based on their respective roles in cell regulation, glycosaminoglycan synthesis, antioxidant defense, and collagen synthesis, all of which are vital for the functional regulation of β-defensin 44. Each compound in this class offers a unique perspective on the indirect modulation of β-defensin 44, showcasing the potential of diverse biochemical pathways in influencing protein activity.

In summary, the β-defensin 44 Inhibitors class represents a theoretical approach to modulate the activity of β-defensin 44 indirectly. This class is characterized by its diversity, with each member bringing a unique mode of action to the table. While direct inhibitors are not identified, the indirect modulation via various biochemical and physiological pathways presents a novel approach to understanding and potentially influencing the function of β-defensin 44. This class underscores the complexity of biological systems and the potential of indirect modulation as a strategy to understand and influence protein function.

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Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

May enhance β-defensin 44 expression through its role in immune modulation and skin barrier function.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Could upregulate β-defensin 44 activity by bolstering skin integrity and immune response.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Might influence β-defensin 44 through differentiation and proliferation of epithelial cells.

Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)

10417-94-4sc-200766
sc-200766A
100 mg
1 g
$102.00
$423.00
(0)

Could modulate inflammatory responses, potentially affecting β-defensin 44 expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

May regulate immune function, indirectly influencing β-defensin 44 activity.

Lactoferrin

146897-68-9sc-394420
sc-394420A
sc-394420B
sc-394420C
10 mg
50 mg
100 mg
1 g
$120.00
$400.00
$569.00
$1465.00
(1)

Could enhance β-defensin 44 through its immunomodulatory and antimicrobial properties.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Might modulate β-defensin 44 indirectly by affecting NF-kB pathway, crucial for immune response.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

May regulate inflammatory pathways and oxidative stress, potentially influencing β-defensin 44.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Could modulate β-defensin 44 through sirtuin pathways, impacting cell regulation and immunity.

D-Glucosamine

3416-24-8sc-278917A
sc-278917
1 g
10 g
$197.00
$764.00
(0)

Might influence β-defensin 44 activity by modulating glycosaminoglycan synthesis in skin cells.