Molecular structure of Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3), CAS Number: 10417-94-4
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) (CAS 10417-94-4)
Alternate Names:
Eicosapentaenoic Acid; Icosapent
Application:
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) is a 5-LO inhibitor
CAS Number:
10417-94-4
Purity:
≥98%
Molecular Weight:
302.45
Molecular Formula:
C20H30O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) is a polyunsaturated omega-3 fatty acid that is a subject of considerable interest in lipidomic research. It is extensively studied for its role in the biosynthesis of eicosanoids, which are lipid mediators involved in inflammatory and immune responses. In nutritional research, Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) is investigated for its influence on the lipid composition of cell membranes and its competition with arachidonic acid for incorporation into phospholipids. Its involvement in the modulation of signal transduction processes in cells is also a key area of study. Furthermore, researchers utilize Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) in studies focusing on the regulation of lipid metabolism enzymes, including desaturases and elongases, to understand the intricate pathways of lipid biosynthesis and homeostasis.
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) (CAS 10417-94-4) References
- [Effect of various unsaturated fatty acids on the stability of the erythrocyte membrane in the rat]. | Roth, HP. and Kirchgessner, M. 1992. Ann Nutr Metab. 36: 113-20. PMID: 1354951
- Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. | Wada, M., et al. 2007. J Biol Chem. 282: 22254-66. PMID: 17519235
- Differential effects of eicosapentaenoic acid and oleic acid on lipid synthesis and secretion by HepG2 cells. | Homan, R., et al. 1991. J Lipid Res. 32: 231-41. PMID: 2066660
- Effects of eicosapentaenoic acid (EPA) treatment on insulin sensitivity in an animal model of diabetes: improvement of the inflammatory status. | Figueras, M., et al. 2011. Obesity (Silver Spring). 19: 362-9. PMID: 20885391
- Effects of eicosapentaenoic acid versus docosahexaenoic acid on serum lipids: a systematic review and meta-analysis. | Wei, MY. and Jacobson, TA. 2011. Curr Atheroscler Rep. 13: 474-83. PMID: 21975919
- Eicosapentaenoic acid metabolism in brain microvessel endothelium: effect on prostaglandin formation. | Yerram, NR., et al. 1989. J Lipid Res. 30: 1747-57. PMID: 2559136
- Prescription omega-3 fatty acid products containing highly purified eicosapentaenoic acid (EPA). | Brinton, EA. and Mason, RP. 2017. Lipids Health Dis. 16: 23. PMID: 28137294
- Eicosapentaenoic Acid-Enriched High-Density Lipoproteins Exhibit Anti-Atherogenic Properties. | Tanaka, N., et al. 2018. Circ J. 82: 596-601. PMID: 28652532
- Effects of eicosapentaenoic acid and docosahexaenoic acid on anxiety-like behavior in socially isolated rats. | Oshima, Y., et al. 2018. Biosci Biotechnol Biochem. 82: 716-723. PMID: 29191085
- Eicosapentaenoic acid supplemented to in vitro maturation medium results in lesser lipid content and intracellular reactive oxygen species in blastocysts of cattle. | Nikoloff, N., et al. 2021. Anim Reprod Sci. 229: 106765. PMID: 33989912
- Eicosapentaenoic acid (EPA) production from microorganisms: a review. | Bajpai, P. and Bajpai, PK. 1993. J Biotechnol. 30: 161-83. PMID: 7764033
- Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages. | Kobayashi, J., et al. 1995. Prostaglandins Leukot Essent Fatty Acids. 52: 259-62. PMID: 7784475
- Effects of eicosapentaenoic acid on tumour growth and cachexia in mouse colon cancer. | Tisdale, MJ., et al. 1994. World Rev Nutr Diet. 76: 86-8. PMID: 7856243
Inhibitor of:
β-defensin 44, 5-LO, AGP-2, APOL (Apolipoprotein L), CD203a, EHHADH, Endothelial Lipase, ESAM, FACL5, Fibrinogen γ, KRTAP10-9, Ox-LDL R-1, PEDF, Peroxin 11α, PM20D1, and SEC14L4.Activator of:
α-defensin 2, β-defensin 48, 11β-HSD1L, 15-LO2, 17β-HSD12, 4833423E24Rik, 4930451C15Rik, 6130401L20Rik, 9330182L06Rik, AADACL3, ACAD-11, ACOT7, ACOX2, ACSBG2, ACSM2B, ACSM5, ACSVL6, Angptl1, ANKRD23, Annexin A10, apoA-I, apoA-IV, apoA-V, apoAL, apoM, ARHGEF15, ASAHL, ATP8B2, Aytl1b, B-FABP, Bmx, C/EBP β, C18orf19, C1s, C6, CCDC69, CD64, Ces1c, Chymostatin, Collectin 43, colostrinin, Conglutinin, cPLA2, CPTI-M, CRB1, CRP, CSN7a, CYP4A1, CYP4A11, CYP4A22, CYP4F3, CYP4V3, CYP4X1, Cystinosin, DDHD2, DENND2C, DGAT1, DNAJC25-GNG10, DNASE1L3, DPRP2, ECEL1, EDG-3, EDG-4, EG434676, Elastase-3B, ELOVL4, EMP-1, encephalopsin, Enterokinase HC, Epidermis-type 12-LO, epsin2, FABP12, FACL5, FACL6, FADS1, FADS3, FADS6, FGF-14, ficolin B, Filaggrin, FIT2, Flg, Gα 16, Gα t12, GBP6, GCET2, Glycophorin A, GNPAT, GP49A, GPR116, GPR120, group IID sPLA2, group IIE sPLA2, Hepatic Lipase, HGFL α, HM74A, HNF-4γ, HoxB9, HYAL6, I-FABP, IAP, IARS2, IgA chain C, IL-22, INPP5J, INSIG-1, Integrin β7, Keratin 31, Keratin 72, KRTAP1, KRTAP10-10, KRTAP10-11, KRTAP10-2, KRTAP10-6, KRTAP10-8, KRTAP12-4, KRTAP13-3, KRTAP19-7, KRTAP20-2, KRTAP5-3, KRTAP8-2, KRTAP9-L3, Lce1l, LDL, LDLR, Lipin-2, Lipocalin-15, Lipocalin-L1, LOC100039801, LPAAT-α, LPCAT1, LPCAT2, LPD lipase, LPL, LRIF, LRP130, LRRC10, Ly-GDI, LYPLAL1, MBOAT4, MBOAT5, MCAD, MCCB, MKP-1, MLTK, MrgB13, MRP-63, MSMP, Mucin 10, Mucin 3A, MULK, MYH14, Myotilin, Na+/K+-ATPase α1, NDUFAF1, neurexin II, NHE-4, NrCAM, OAT5, Occludin, Oculospanin, OLFML1, OR5H2, OR5K4, ORP-1, OTTMUSG00000018260, p60 Mitochondrial Marker, PC-PLD, PC-TP, PEAR1, PEMT, peropsin, Peroxin 10, Peroxin 11γ, Peroxin 12, Peroxin 13, Peroxin 14, Peroxin 5, Peroxin 5R, Peroxisome 26, PGM 3, PHYH, PIG-V, Pin1, PLEKHG3, Pmp24, Podocin, PP2A-B55-γ, PPAR alpha, PRCD, PTPLB, RasGRP3, rhodopsin, RLD-1, RNFT1, ROM-K, SAP-1, SCD, SCD2, SCD5, SEMA4C, SerpinB1, SHIP-2, SLC22A12, SLC25A29, SLC26A9, SMCR7, SPAG11B, SPLUNC3, Spot 14, SREB1, StARD10, Synaptotagmin VIII, Syndecan-4, T-FABP, TBC1D1, TFPI, TFPI-2, TIP47, TMPRSS11E, TREM-2a, TREM-2b, TTC7A, TXA synthase, WAVE1, WT1, Y14_RBM8, and ZADH1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3), 100 mg | sc-200766 | 100 mg | $102.00 | |||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3), 1 g | sc-200766A | 1 g | $423.00 |