Lactoferrin (CAS 146897-68-9)
Alternate Names:
Lactotransferrin
Application:
Lactoferrin is an antimicrobial and antifungal peptide
CAS Number:
146897-68-9
Purity:
≥92%
Molecular Weight:
90 kDa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Lactoferrin is a protein found abundantly in cow milk and is homologous to human lactoferrin. This protein is extensively studied in nutritional and biochemical research due to its ability to bind and transport iron ions, thus playing a significant role in iron homeostasis. In addition to its iron-binding properties, Lactoferrin (Bovine) is also of interest for its interaction with bacterial pathogens, as it may act to exhibit antibacterial activity, which is subject to research on the mechanisms of innate immunity. The protein′s influence on cell growth and differentiation makes it a relevant model in cellular biology studies. Researchers also investigate the potential of Lactoferrin (Bovine) to bind to other metal ions and its structural response to such interactions, contributing to a broader understanding of metal-protein biochemistry.
Lactoferrin (CAS 146897-68-9) References
- Growth responses of coliform bacteria to purified immunoglobulin G from cows immunized with ferric enterobactin receptor FepA. | Lin, J., et al. 1999. J Dairy Sci. 82: 86-92. PMID: 10022010
- Purification and characterization of PCR-inhibitory components in blood cells. | Al-Soud, WA. and Rådström, P. 2001. J Clin Microbiol. 39: 485-93. PMID: 11158094
- In vitro growth responses of bifidobacteria and enteropathogens to bovine and human lactoferrin. | Griffiths, EA., et al. 2003. Dig Dis Sci. 48: 1324-32. PMID: 12870790
- Prospective estimation of IgG, IgG subclass and IgE antibodies to dietary proteins in infants with cow milk allergy. Levels of antibodies to whole milk protein, BLG and ovalbumin in relation to repeated milk challenge and clinical course of cow milk allergy. | Høst, A., et al. 1992. Allergy. 47: 218-29. PMID: 1510234
- In vivo effects of bifidobacteria and lactoferrin on gut endotoxin concentration and mucosal immunity in Balb/c mice. | Griffiths, EA., et al. 2004. Dig Dis Sci. 49: 579-89. PMID: 15185861
- Iron uptake from transferrin and lactoferrin by rat intestinal brush-border membrane vesicles. | Kawakami, H., et al. 1990. Am J Physiol. 258: G535-41. PMID: 2333967
- Integrated system for temperature-controlled fast protein liquid chromatography. II. Optimized adsorbents and 'single column continuous operation'. | Cao, P., et al. 2015. J Chromatogr A. 1403: 118-31. PMID: 26051083
- Temperature-Switchable Agglomeration of Magnetic Particles Designed for Continuous Separation Processes in Biotechnology. | Paulus, AS., et al. 2015. ACS Appl Mater Interfaces. 7: 14279-87. PMID: 26069936
- A Lectin Purified from Blood Red Bracket Mushroom, Pycnoporus sanguineus (Agaricomycetidae), Mycelium Displayed Affinity Toward Bovine Transferrin. | Albores, S., et al. 2016. Int J Med Mushrooms. 18: 67-74. PMID: 27279446
- Studying Lactoferrin N-Glycosylation. | Karav, S., et al. 2017. Int J Mol Sci. 18: PMID: 28425960
- Dynamics and energetics of bovine lactoferrin and phenylmethane dyes interaction followed by surface plasmon resonance. | Campos de Paula, HM., et al. 2022. Colloids Surf B Biointerfaces. 219: 112794. PMID: 36162180
- Lactoferrin receptors in intestinal brush border membranes. | Lönnerdal, B. 1994. Adv Exp Med Biol. 357: 171-5. PMID: 7762428
- Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment. | Yamauchi, K., et al. 1993. Infect Immun. 61: 719-28. PMID: 8423097
Inhibitor of:
α-1-Microglobulin, β-defensin 33, β-defensin 44, BPIL3, C. abortus LPS, CNIH4, EG434726, EG434727, EG434729, ferritin, Hep A sAg, LL-37, Lysozyme C, LYZL4, mito293Tndrial ferritin, and Rotavirus capsid.Activator of:
α-defensin 2, α-defensin 4, β-defensin 1, β-defensin 109, β-defensin 115, β-defensin 116, β-defensin 118, β-defensin 119, β-defensin 12, β-defensin 121, β-defensin 123, β-defensin 125, β-defensin 127, β-defensin 128, β-defensin 133, β-defensin 134, β-defensin 135, β-defensin 136, β-defensin 137, β-defensin 15, β-defensin 32, β-defensin 7, 9530003J23Rik, BOCT, CRS1C-2, CRS1C-3, CRS4C-2, E330017A01Rik, EG665956, ferritin heavy chain, FRRS1, Gastrokine 2, HFE, IgA chain C, lactoferrin, Matriptase-2, mCST E2, NRAMP 2, OTTMUSG00000018260, Rotavirus virus p42, Salmonella LPS, Shigatoxin, and VacA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lactoferrin, 10 mg | sc-394420 | 10 mg | $122.00 | |||
Lactoferrin, 50 mg | sc-394420A | 50 mg | $408.00 | |||
Lactoferrin, 100 mg | sc-394420B | 100 mg | $580.00 | |||
Lactoferrin, 1 g | sc-394420C | 1 g | $1494.00 |