β-defensin 3B Inhibitors
β-Defensin 3B inhibitors represent a class of chemical compounds that specifically target and inhibit the activity of β-defensin 3B, a member of the defensin family of antimicrobial peptides. β-Defensin 3B is part of the innate immune system, characterized by its ability to disrupt microbial membranes and its role in modulating immune responses. The inhibitors of β-defensin 3B are designed to bind to specific sites on the peptide, blocking its activity and preventing it from interacting with its target molecules. These inhibitors can be peptides, small molecules, or other types of chemical entities that have been structurally optimized to achieve high affinity and selectivity for β-defensin 3B. The study of these inhibitors often involves detailed structural biology techniques, such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy, to understand the binding interactions and conformational changes that occur upon inhibition.
Research into β-defensin 3B inhibitors also explores their biochemical properties, such as their stability, solubility, and ability to permeate cell membranes, as these factors are critical for their effectiveness in inhibiting β-defensin 3B under various conditions. The development and characterization of these inhibitors require a multidisciplinary approach, incorporating aspects of synthetic chemistry, biochemistry, and molecular biology. Techniques such as high-throughput screening, rational drug design, and computational modeling are often employed to identify and optimize potential inhibitors. Furthermore, the study of β-defensin 3B inhibitors contributes to a broader understanding of protein-peptide interactions, providing insights into the structural and functional dynamics of β-defensins and their role in immune response modulation. This field of research is critical for expanding the knowledge of molecular interactions and regulatory mechanisms within the immune system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been found to inhibit the expression of various antimicrobial peptides, potentially including β-defensin 3, by modulating specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has been reported to inhibit the expression of certain antimicrobial peptides, potentially including β-defensin 3, by modulating specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin has shown inhibitory effects on the expression of specific antimicrobial peptides, potentially including β-defensin 3, by modulating signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein has been found to modulate the expression of antimicrobial peptides, potentially including β-defensin 3, by interfering with specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $31.00 $41.00 $159.00 $286.00 | 12 | |
Baicalein has been reported to inhibit the expression of certain antimicrobial peptides, potentially including β-defensin 3, by modulating specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin has been found to inhibit the expression of specific antimicrobial peptides, potentially including β-defensin 3, by modulating specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate (EGCG) has been reported to modulate the expression of certain antimicrobial peptides, potentially including β-defensin 3, by interfering with specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Piperine | 94-62-2 | sc-205809 sc-205809A | 5 g 25 g | $36.00 $143.00 | 3 | |
Piperine has been studied for its potential to inhibit the expression of various antimicrobial peptides, including β-defensin 3, by modulating specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin has demonstrated the ability to inhibit the expression of specific antimicrobial peptides, potentially including β-defensin 3, by modulating specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane has been investigated for its potential to modulate the expression of antimicrobial peptides, potentially including β-defensin 3, by interfering with specific signaling pathways involved in the regulation of antimicrobial peptide expression. | ||||||