BC046404 Activators
BC046404 Activators are a diverse set of chemical compounds that influence various cellular signaling pathways, leading to the potential enhancement of BC046404's activity. Forskolin and IBMX both increase intracellular cAMP levels, which can activate PKA and potentially lead to phosphorylation events that enhance BC046404. In a similar vein, PMA activates PKC, potentially phosphorylating BC046404 or related proteins to augment its activity. Ionomycin raises intracellular calcium levels, which might activate calcium-dependent kinases that could phosphorylate and activate BC046404. Okadaic acid, by inhibiting protein phosphatases, may lead to an increased phosphorylation state within the cell, indirectly promoting BC046404 activity.
Continuing with the theme of kinase regulation, EGCG as a kinase inhibitor could reduce negative regulatory influences on BC046404, while LY294002, PD 98059, SB203580, and U0126 modulate various aspects of the MAPK signaling pathway, potentially creating a cellular environment that enhances BC046404 activity. KN-93 targets CaMKII, a kinase that may indirectly affect BC046404 activity through Ca2+/CaM-dependent signaling pathways. Lastly, Anisomycin serves as a JNK activator, which might modulate the JNK signaling pathway to indirectly promote the enhancement of BC046404, likely through stress response pathways. Collectively, these activators influence a network of biochemical pathways that can lead to the enhanced functional activity of BC046404 without directly increasing its expression or acting as direct ligands.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, preventing cAMP degradation. This leads to increased cAMP levels, indirectly enhancing PKA activity, which could phosphorylate BC046404 or its partners, potentially enhancing BC046404 activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a PKC activator, which could phosphorylate BC046404 or related proteins, potentially enhancing BC046404's activity through protein kinase C mediated pathways. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, which can activate calcium-dependent protein kinases that potentially phosphorylate BC046404, leading to its activation. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic acid is an inhibitor of protein phosphatases PP1 and PP2A, leading to increased phosphorylation levels within the cell. This could indirectly enhance the phosphorylation and activity of BC046404. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a kinase inhibitor with a broad target range, which could inhibit kinases that negatively regulate BC046404, thereby potentially enhancing BC046404 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that could alter signaling pathways to indirectly enhance the activity of BC046404 by modulating downstream effects of PI3K inhibition, such as Akt signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD 98059 is a MEK inhibitor that could shift the signaling equilibrium and potentially enhance BC046404 activity by altering the MAPK/ERK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, potentially altering signaling dynamics to favor pathways that enhance BC046404 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK1/2 inhibitor, which could lead to an indirect enhancement of BC046404 by modulating the MAPK/ERK signaling pathway. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
KN-93 is an inhibitor of CaMKII (calcium/calmodulin-dependent protein kinase II), which might indirectly enhance BC046404 activity by influencing Ca2+/CaM signaling pathways. | ||||||