BAALC Activators
BAALC activators encompass a range of chemical compounds that can either directly enhance the functional activity of BAALC or indirectly trigger signaling events leading to its activation. These compounds operate primarily via the cAMP-dependent protein kinase (PKA) pathway, a signaling cascade that BAALC is known to interact with. Activators of this class enhance the functional activity of BAALC by increasing intracellular cAMP levels, which in turn can activate PKA. PKA is known to interact with BAALC and can enhance its functional activity.
Activators of this class can lead to the activation of BAALC due to their inhibitory effects on adenylate cyclase and PKA, respectively. These compounds reduce cAMP levels and PKA activity, which can paradoxically activate BAALC due to the complex feedback mechanisms inherent in the signaling pathway. This illustrates the intricate interplay of regulatory mechanisms in cellular signaling pathways. Although these compounds have inhibitory effects on certain enzymes or pathways, they can indirectly enhance the functional activity of BAALC by triggering these feedback mechanisms. These diverse compounds, by acting on different components of the same pathway, collectively contribute to the functional activation of BAALC.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, leading to increased levels of cyclic AMP (cAMP). BAALC is known to interact with the cAMP-dependent protein kinase (PKA) pathway. Enhanced cAMP levels can trigger PKA, leading to the activation of BAALC. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a beta-adrenergic receptor agonist. This receptor activation increases cAMP levels, which stimulates PKA. PKA can activate BAALC which is involved in the same signaling cascade. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram inhibits phosphodiesterase 4 (PDE4), leading to increased cAMP levels. The elevated cAMP triggers PKA which, in turn, activates BAALC. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX inhibits phosphodiesterases non-selectively and causes an increase in cAMP levels. The accumulation of cAMP triggers PKA, which can activate BAALC. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates beta-adrenergic receptors. This receptor activation increases cAMP levels, which can stimulate PKA. PKA can activate BAALC which is part of this signaling pathway. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $326.00 $485.00 | 3 | |
Norepinephrine activates beta-adrenergic receptors, leading to increased cAMP levels. These levels stimulate PKA, which can activate BAALC. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 is a prostaglandin that stimulates adenylate cyclase to increase cAMP levels. The resulting cAMP accumulation triggers PKA, which can activate BAALC. | ||||||
SQ 22536 | 17318-31-9 | sc-201572 sc-201572A | 5 mg 25 mg | $95.00 $363.00 | 13 | |
SQ 22536 is an adenylate cyclase inhibitor. However, the reduction of cAMP levels and subsequent decrease in PKA activity can paradoxically lead to the activation of BAALC due to the complex feedback mechanisms in the signaling pathway. | ||||||
Papaverine | 58-74-2 | sc-279951 sc-279951A sc-279951B | 10 mg 50 mg 100 mg | $153.00 $265.00 $459.00 | ||
Papaverine, a PDE inhibitor, raises cellular cAMP levels. The increased cAMP triggers PKA, which can activate BAALC. | ||||||
Dobutamine | 34368-04-2 | sc-507555 | 100 mg | $295.00 | ||
Dobutamine is a beta-1 adrenergic receptor agonist that increases cAMP levels, which in turn stimulate PKA. PKA can activate BAALC which is part of this signaling pathway. | ||||||