BAALC Inhibitors refers to a specific class of chemical compounds designed to target and modulate the activity of the Brain and Acute Leukemia, Cytoplasmic (BAALC) protein. BAALC is a cytoplasmic protein that has been implicated in various cellular processes, particularly in the context of hematopoiesis and the development of certain malignancies. The inhibitors belonging to this chemical class are meticulously crafted to interfere with the function of BAALC, exerting their effects at the molecular level. These inhibitors are designed based on an in-depth understanding of the structural and biochemical characteristics of the BAALC protein.
BAALC Inhibitors often possess a distinct configuration that allows them to bind selectively to the active sites or specific regions of the BAALC protein. The binding interaction between the inhibitor and BAALC is crucial for disrupting the normal physiological functions of the protein, ultimately leading to altered cellular responses. Researchers employ various techniques, such as structural biology and medicinal chemistry, to design BAALC Inhibitors with enhanced specificity and potency. The development of these inhibitors represents a significant advancement in the field of molecular pharmacology, offering a precise tool for probing the functional role of BAALC and its involvement in cellular processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Imatinib inhibits BCR-ABL, a fusion protein involved in certain leukemias, which can indirectly affect BAALC by reducing the overall leukemogenic signaling. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib is a multi-kinase inhibitor that can affect BAALC indirectly by inhibiting SRC family kinases, thereby reducing the activity of multiple downstream pathways. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $205.00 $405.00 | 9 | |
Similar to Imatinib, Nilotinib inhibits BCR-ABL and can thus impact BAALC indirectly. | ||||||
PKC-412 | 120685-11-2 | sc-200691 sc-200691A | 1 mg 5 mg | $51.00 $112.00 | 10 | |
Midostaurin is a multi-kinase inhibitor that can impact BAALC indirectly by inhibiting FLT3, KIT, and other kinases. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Sorafenib inhibits multiple kinases including RAF and VEGFR, which can indirectly impact BAALC by reducing cell proliferation and angiogenesis. | ||||||
Sunitinib Malate | 341031-54-7 | sc-220177 sc-220177A sc-220177B | 10 mg 100 mg 3 g | $193.00 $510.00 $1072.00 | 4 | |
Sunitinib inhibits multiple kinases, including VEGFR and PDGFR, which can indirectly impact BAALC by inhibiting cell proliferation and angiogenesis. | ||||||
Regorafenib | 755037-03-7 | sc-477163 sc-477163A | 25 mg 50 mg | $320.00 $430.00 | 3 | |
Regorafenib is a multi-kinase inhibitor that can impact BAALC by inhibiting kinases involved in cell proliferation and angiogenesis. | ||||||
AP 24534 | 943319-70-8 | sc-362710 sc-362710A | 10 mg 50 mg | $172.00 $964.00 | 2 | |
Ponatinib inhibits BCR-ABL and other kinases, which can indirectly affect BAALC. | ||||||
Lenvatinib | 417716-92-8 | sc-488530 sc-488530A sc-488530B | 5 mg 25 mg 100 mg | $178.00 $648.00 $1657.00 | 3 | |
Lenvatinib inhibits multiple kinases, including VEGFR, which can indirectly impact BAALC by inhibiting cell proliferation and angiogenesis. | ||||||
Pazopanib | 444731-52-6 | sc-396318 sc-396318A | 25 mg 50 mg | $127.00 $178.00 | 2 | |
Pazopanib inhibits multiple kinases, including VEGFR and PDGFR, which can indirectly impact BAALC by inhibiting cell proliferation and angiogenesis. |