Papaverine CAS: 58-74-2
MF: C20H21NO4
MW: 339.38
A phosphodiesterase inhibitor.

Papaverine (CAS 58-74-2)

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Alternate Names: Cerespan; Papanerine
Application: Papaverine is a phosphodiesterase inhibitor
CAS Number: 58-74-2
Purity: 97%
Molecular Weight: 339.38
Molecular Formula: C20H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Papaverine is a phosphodiesterase inhibitor shown to be partially selective for PDE10A.

Physical State :
Solid
Solubility :
Soluble in water (partly miscible), hot benzene, glacial acetic acid, acetone, ethanol (~0.1 mg/ml), DMSO (~5 mg/ml), DMF (~5 mg/ml), and chloroform. Insoluble in ether.
Storage :
Store at -20° C
Melting Point :
146-147° C
Boiling Point :
483.24° C at 760 mmHg (Predicted)
Density :
1.34 g/cm3 at 20° C
Refractive Index :
n20D 1.59 (Predicted)
IC50 :
PDE10A: IC50 = 17 nM (human); Mycobacterium tuberculosis: EC5050 = 3010 nM (human); CYP2C19: IC50 = 762 nM (human); Phosphodiesterase: IC50 = 13 µM
Ki Data :
PDE3A: Ki= 279 nM (human); PDE3B: Ki= 417 nM (human)
pK Values :
pKb: 6.32 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
NW8450000
PubChem CID :
4680
Merck Index :
14: 7019
MDL Number :
MFCD00024138
EC Number :
200-397-2
Beilstein Registry :
312930
SMILES :
COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC

Download SDS (MSDS)

Certificate of Analysis

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