AXUD1 Inhibitors
AXUD1 inhibitors are a class of chemical compounds that specifically target the AXUD1 protein, a gene regulator involved in various cellular processes such as differentiation, growth, and apoptosis. AXUD1, also known as AXIN1 up-regulated 1, is a transcriptional target of the Wnt/β-catenin signaling pathway and plays a role in modulating gene expression in response to external signaling cues. It functions by interacting with different transcriptional complexes and regulatory proteins, influencing the activation or repression of specific genes. Inhibitors of AXUD1 disrupt its activity, affecting its ability to regulate downstream genes and pathways critical for cellular homeostasis and development.
The mechanism of AXUD1 inhibitors involves blocking its interactions with other proteins or its ability to bind to promoter regions of target genes. These inhibitors can either bind directly to AXUD1, preventing it from participating in transcriptional complexes, or they may alter its structural conformation, rendering it ineffective in gene regulation. By inhibiting AXUD1 function, these compounds alter the transcriptional programs that the protein controls, providing insights into the molecular mechanisms underlying cellular differentiation and signaling processes. Researchers use AXUD1 inhibitors to study the specific roles of this protein in various biological contexts, particularly in understanding how it contributes to the regulation of gene expression in response to pathways like Wnt. This helps illuminate broader regulatory networks involved in cellular growth, apoptosis, and tissue development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a kinase inhibitor that could possibly inhibit CSRNP1 by altering the activity of transcription factors and proteins that may interact with CSRNP1, thus affecting its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is an inhibitor of PI3K, which could possibly inhibit CSRNP1 by impacting cellular processes that are associated with CSRNP1's role in gene expression regulation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK, which could possibly inhibit CSRNP1 by affecting the MAPK/ERK pathway, modifying the activity of transcription factors or other proteins involved with CSRNP1's function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK, which could possibly inhibit CSRNP1 by influencing transcriptional regulation through modifying the activity of proteins that interact with or regulate CSRNP1. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, which could possibly inhibit CSRNP1 by impacting stress response pathways and potentially modify the regulatory context in which CSRNP1 operates. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor that could possibly inhibit CSRNP1 by affecting signaling pathways that modulate the roles played by CSRNP1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, which could possibly inhibit CSRNP1 by being involved in cell growth and protein synthesis, potentially affecting the processes that CSRNP1 regulates. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor, which could possibly inhibit CSRNP1 by influencing gene expression patterns and thereby affect CSRNP1's activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor, which could possibly inhibit CSRNP1 by leading to altered chromatin states and impact gene expression regulation mechanisms where CSRNP1 might play a role. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is a proteasome inhibitor, which could possibly inhibit CSRNP1 by influencing the degradation of proteins that regulate or interact with CSRNP1, affecting its function. | ||||||