apoOL Inhibitors
Common apoOL Inhibitors include, but are not limited to Antimycin A
APOOL inhibitors encompass a range of compounds that, while not directly targeting APOOL, can influence its function by altering mitochondrial dynamics or health. Among these, some inhibitors, like Mdivi-1, directly intervene in mitochondrial fission and fusion dynamics. Others, like CCCP or FCCP, compromise mitochondrial health by uncoupling oxidative phosphorylation.
By affecting the electron transport chain, compounds like Antimycin A, Rotenone, and Azide can also indirectly impact APOOL function. The inhibition of glycolysis by 2-Deoxy-D-glucose reduces substrate availability for mitochondria, and agents like Actinonin that target mitochondrial protein homeostasis can indirectly influence APOOL. Given the central role of mitochondria in cellular health, energy production, and signaling, compounds affecting its dynamics can have wide-ranging impacts on numerous proteins, including APOOL.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Inhibits mitochondrial division by targeting the mitochondrial division DRP1, thus can indirectly affect APOOL function. | ||||||
Carbonyl Cyanide m-Chlorophenylhydrazone | 555-60-2 | sc-202984A sc-202984 sc-202984B | 100 mg 250 mg 500 mg | $77.00 $153.00 $240.00 | 8 | |
Uncouples mitochondrial oxidative phosphorylation, affecting mitochondrial health and potentially APOOL functionality. | ||||||
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Inhibits ATP synthase in mitochondria, potentially impacting cristae dynamics and indirectly APOOL function. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Inhibits complex III of the electron transport chain, potentially affecting mitochondrial health and APOOL functionality. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $259.00 | 41 | |
Inhibits complex I of the mitochondrial electron transport chain, possibly influencing APOOL indirectly. | ||||||
FCCP | 370-86-5 | sc-203578 sc-203578A | 10 mg 50 mg | $94.00 $355.00 | 46 | |
Another mitochondrial uncoupler, potentially affecting APOOL by compromising mitochondrial health. | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $250.00 | 3 | |
Potassium ionophore affecting mitochondrial membrane potential, potentially impacting APOOL indirectly. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Inhibits glycolysis, leading to reduced substrate for mitochondria, possibly influencing APOOL indirectly. | ||||||
Sodium azide | 26628-22-8 | sc-208393 sc-208393B sc-208393C sc-208393D sc-208393A | 25 g 250 g 1 kg 2.5 kg 100 g | $43.00 $155.00 $393.00 $862.00 $90.00 | 8 | |
Inhibits cytochrome c oxidase, affecting electron transport chain and potentially influencing APOOL. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $170.00 $385.00 | 3 | |
Inhibits mitochondrial peptide deformylase, potentially affecting mitochondrial protein homeostasis and APOOL indirectly. | ||||||