ANKRD18A Activators
ANKRD18A activators represent a specialized class of chemical compounds that interact with the ANKRD18A protein, also known as the ankyrin repeat domain-containing protein 18A. This protein is characterized by the presence of multiple ankyrin repeat motifs, which are known for their role in mediating protein-protein interactions and cellular signaling pathways. ANKRD18A is involved in various cellular processes, including the regulation of cytoskeletal dynamics and intracellular transport. The design of ANKRD18A activators is often focused on enhancing the protein's functional capacity, promoting its stability, or increasing its interaction with specific binding partners. These compounds are typically small molecules or peptides that exhibit high affinity for ANKRD18A, allowing for selective modulation of its activity.
The synthesis of ANKRD18A activators involves diverse chemical strategies, including combinatorial chemistry and structure-activity relationship (SAR) studies, to optimize their binding properties and functional outcomes. These activators can influence cellular processes by modulating the conformational states of ANKRD18A or enhancing its interaction with other proteins in signaling cascades. The exploration of ANKRD18A activators contributes to a broader understanding of the protein's biological roles and interactions within the cell. In addition, studying these activators aids in deciphering the underlying mechanisms governing cellular responses to various stimuli, thus enriching the knowledge base within the field of biochemical research. Overall, ANKRD18A activators serve as essential tools for investigating the multifaceted roles of the ANKRD18A protein in various biological contexts.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Azacitidine, a DNA methylation inhibitor, may induce ANKRD18A by demethylating its promoter region, leading to gene activation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, an NAD-dependent deacetylase, which can modify chromatin and alter gene expression, potentially affecting ANKRD18A. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and affects transcription factor binding, possibly leading to changes in gene expression including ANKRD18A. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine, by altering endosomal and lysosomal pH, can affect cellular signaling and potentially the expression of genes like ANKRD18A. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide causes DNA damage by inhibiting topoisomerase II, which could lead to a DNA damage response that may include ANKRD18A upregulation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
HDAC inhibitors such as Valproic acid induce hyperacetylation of histones, potentially increasing the expression of ANKRD18A. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
ATRA, by binding to retinoic acid receptors, can modulate gene expression, which may include the ANKRD18A gene. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate multiple signaling pathways and may influence the transcription of genes including ANKRD18A. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a glucocorticoid, can regulate gene expression through glucocorticoid response elements, potentially affecting ANKRD18A. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $107.00 | 3 | |
Spironolactone, as an aldosterone antagonist, might indirectly affect gene expression profiles, including ANKRD18A. | ||||||