Date published: 2026-4-5

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α-synuclein Antibodies

Santa Cruz Biotechnology offers a broad range of α-synuclein monoclonal antibodies for investigating neurodegenerative diseases. Multiple detection methods are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). α-Synuclein is a presynaptic protein essential for synaptic function and neurotransmitter release. The aggregation of α-synuclein represents a key characteristic of several neurodegenerative disorders, including Parkinson's disease and dementia with Lewy bodies. Research focused on α-synuclein continues to reveal new insights about disease progression and potential treatments. Scientists worldwide rely on highly specific monoclonal antibodies to examine α-synuclein's role in both healthy and diseased states. Investigating α-synuclein's molecular mechanisms helps identify new therapeutic targets and biomarkers. Current research explores how α-synuclein modifications influence cellular processes and disease development. Santa Cruz Biotechnology monoclonal antibodies for α-synuclein support researchers in advancing scientific understanding of neurodegenerative diseases and potential therapeutic approaches.

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α-synuclein Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

alpha Synuclein Antibody (211)

sc-12767mouse IgG1 κ121-125 (h)WB, IP, IF, IHC(P)h
220
(29)

alpha Synuclein Antibody (2B2D1)

sc-53955mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
8
(9)

alpha Synuclein Antibody (3H2897)

sc-69977mouse IgG1FL (h)WB, IP, IF, IHC(P)m, r, h
39
(10)

alpha Synuclein Antibody (LB 509)

sc-58480mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
30
(5)

alpha Synuclein Antibody (Syn 204)

sc-32280mouse IgG2a κ(h)WB, IP, IF, IHC(P)h
9
(8)

alpha Synuclein Antibody (3G282)

sc-69978mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(1)

alpha Synuclein Antibody (D-10)

sc-515879mouse IgG2a κ112-140 (h)WB, IP, IF, ELISAm, r, h
4
(1)

alpha/beta Synuclein Antibody (Syn 202)

sc-32281mouse IgG2a κ(h)WB, IP, IF, IHC(P)m, r, h
3
(3)

nitrated alpha Synuclein Antibody (Syn514)

sc-32279mouse IgG1 κoxidized α-synuclein (h)WB, IP, IFm, r, h
5
(1)

nitrated alpha Synuclein Antibody (4H316)

sc-71703mouse IgG1 κ(h)WB, IP, IFm, r, h

new

(1)

nitrated alpha/beta Synuclein Antibody (4H317)

sc-71702mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(1)

nitrated alpha/beta Synuclein Antibody (Syn12)

sc-32278mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(1)

α-synuclein CRISPR Knockout, HDR and Double Nickase Plasmids

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alpha Synuclein Double Nickase Plasmid (m)

sc-423051-NICmGene KnockoutPuromycin0
(0)

α-synuclein CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

alpha Synuclein CRISPR Activation Plasmid (m)

sc-423051-ACTmGene ActivationPuro, Blast, Hygro0
(0)

α-synuclein siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

alpha Synuclein siRNA (h)

sc-29619hGene SilencingN/A
11
(0)

alpha Synuclein shRNA Plasmid (h)

sc-29619-SHhGene SilencingPuromycin
11
(0)

alpha Synuclein shRNA (h) Lentiviral Particles

sc-29619-VhGene SilencingPuromycin
11
(0)

alpha Synuclein siRNA (m)

sc-42286mGene SilencingN/A0
(0)

alpha Synuclein shRNA Plasmid (m)

sc-42286-SHmGene SilencingPuromycin0
(0)

alpha Synuclein shRNA (m) Lentiviral Particles

sc-42286-VmGene SilencingPuromycin0
(0)