Date published: 2025-12-3

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α-synuclein Substrates

Santa Cruz Biotechnology now offers a broad range of alpha-synuclein substrates for use in various applications. Alpha-synuclein substrates are crucial tools in biochemical and cellular research, particularly for studies focused on protein-protein interactions, protein aggregation, and neurodegenerative diseases. Although the primary focus of these substrates is related to neurobiology, they are widely utilized in various other fields of research, such as molecular biology and biochemistry. Researchers use alpha-synuclein substrates to explore the fundamental mechanisms of protein folding, misfolding, and aggregation, which are essential processes in understanding cellular homeostasis and stress responses. These substrates are also employed in high-throughput screening assays to identify novel protein interactors, monitor post-translational modifications, and investigate the impact of genetic mutations on protein behavior. By enabling the study of alpha-synuclein in controlled environments, these substrates offer invaluable insights into the protein's role in normal cellular function as well as in the pathological processes that can lead to disease. The availability of high-quality alpha-synuclein substrates supports a wide array of experimental approaches, from in vitro biochemical assays to more complex in vivo models. View detailed information on our available alpha-synuclein substrates by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

K 114

872201-12-2sc-204027
sc-204027A
10 mg
50 mg
$154.00
$618.00
1
(1)

K 114 exhibits unique interactions with alpha-synuclein, influencing its aggregation dynamics. This compound stabilizes specific conformations of the protein, altering its fibrillation pathways. K 114's ability to modulate intermolecular forces enhances its reactivity, leading to distinct kinetic profiles in aggregation assays. Its structural features promote selective binding, providing insights into protein misfolding mechanisms and the role of molecular chaperones in neurodegenerative processes.