AChR Activators
Items 11 to 20 of 27 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anabasine hydrochloride | 15251-47-5 | sc-202053 sc-202053A | 25 mg 100 mg | $20.00 $40.00 | ||
Anabasine hydrochloride is a notable alkaloid that selectively interacts with acetylcholine receptors, exhibiting unique binding characteristics due to its nitrogen-containing ring structure. This compound demonstrates a distinct affinity for nicotinic receptors, influencing ion channel conductance and altering neurotransmitter release. Its kinetic profile reveals a moderate activation time, allowing for nuanced modulation of synaptic activity. Additionally, the presence of the hydrochloride moiety enhances solubility, facilitating its interaction in biological systems. | ||||||
(S)-1,2,3,4,5,6-Hexahydro-[2,3′]bipyridinyl hydrochloride | 53912-89-3 | sc-338531 | 500 mg | $260.00 | ||
(S)-1,2,3,4,5,6-Hexahydro-[2,3']bipyridinyl hydrochloride is a bicyclic compound that engages with acetylcholine receptors through specific hydrogen bonding and hydrophobic interactions. Its unique stereochemistry contributes to selective receptor activation, influencing downstream signaling pathways. The compound exhibits rapid kinetics, allowing for swift modulation of synaptic transmission. The hydrochloride form increases its aqueous solubility, promoting effective receptor engagement in various environments. | ||||||
1-Acetyl-4-methylpiperazine hydrochloride | 60787-05-5 | sc-203759 sc-203759A | 10 mg 50 mg | $115.00 $473.00 | ||
1-Acetyl-4-methylpiperazine hydrochloride is a piperazine derivative that interacts with acetylcholine receptors via electrostatic and steric effects, enhancing receptor affinity. Its acetyl group facilitates conformational flexibility, allowing for diverse binding modes. The compound's unique hydrophilic and lipophilic balance aids in membrane permeability, while its hydrochloride form enhances stability and solubility in polar solvents, optimizing its reactivity in biochemical pathways. | ||||||
Aceclidine Hydrochloride | 6109-70-2 | sc-210735 sc-210735A | 1 g 5 g | $225.00 $750.00 | ||
Aceclidine Hydrochloride is a synthetic compound characterized by its ability to selectively interact with acetylcholine receptors, primarily through electrostatic and van der Waals forces. Its unique stereochemistry enhances receptor affinity, facilitating swift conformational changes upon binding. The compound's solubility is significantly improved by its hydrochloride form, allowing for efficient diffusion in diverse environments. Furthermore, its reactivity is influenced by specific functional groups, enabling diverse interactions in biochemical systems. | ||||||
RJR 2429 dihydrochloride | 1021418-53-0 | sc-204237 sc-204237A | 10 mg 50 mg | $192.00 $700.00 | ||
RJR 2429 dihydrochloride is a synthetic compound that exhibits selective modulation of acetylcholine receptors through specific hydrogen bonding and hydrophobic interactions. Its dual hydrochloride form increases solubility and bioavailability, promoting efficient receptor engagement. The compound's unique structural features allow for rapid kinetics in receptor activation, influencing downstream signaling pathways. Additionally, its distinct electronic properties contribute to its reactivity in various biochemical environments. | ||||||
(R,S)-Nornicotine | 5746-86-1 | sc-212644 | 250 mg | $237.00 | ||
(R,S)-Nornicotine is a naturally occurring alkaloid that selectively binds to nicotinic acetylcholine receptors, influencing neurotransmitter release. Its stereochemistry allows for unique interactions with receptor subtypes, modulating ion channel activity. The compound exhibits a notable affinity for specific receptor conformations, leading to differential signaling pathways. Additionally, its hydrophobic regions enhance membrane integration, affecting local microenvironment dynamics and receptor clustering. | ||||||
CCMI | 917837-54-8 | sc-361135 sc-361135A | 10 mg 50 mg | $140.00 $588.00 | 2 | |
CCMI is a synthetic compound that acts as an allosteric modulator of acetylcholine receptors, enhancing receptor sensitivity through specific conformational changes. Its unique structure facilitates interactions with lipid bilayers, promoting membrane fluidity and influencing ion permeability. The compound exhibits distinct reaction kinetics, characterized by rapid binding and unbinding rates, which can fine-tune synaptic transmission and neuronal excitability in various cellular environments. | ||||||
S-(−)-Nicotine ditartrate dihydrate | 6019-06-3 | sc-212381 | 5 g | $400.00 | ||
S-(-)-Nicotine ditartrate dihydrate is a chiral compound that exhibits a strong affinity for nicotinic acetylcholine receptors, engaging in hydrogen bonding and hydrophobic interactions that stabilize receptor-ligand complexes. Its dihydrate form enhances solubility and bioavailability, promoting rapid kinetic responses in receptor activation. The compound's unique stereochemical configuration allows for selective modulation of ion channel dynamics, influencing neurotransmission pathways with precision. | ||||||
Decamethonium bromide | 541-22-0 | sc-239651 | 5 g | $120.00 | ||
Decamethonium bromide is a synthetic compound that acts as a competitive antagonist at nicotinic acetylcholine receptors. Its unique structure allows for strong electrostatic interactions with the receptor's binding site, leading to prolonged receptor blockade. The compound's rigid, elongated conformation facilitates steric hindrance, disrupting normal ion flow. This results in altered synaptic transmission dynamics, influencing neuromuscular signaling pathways and receptor desensitization processes. | ||||||
Cotinine N-β-D-Glucuronide | 139427-57-9 | sc-211139 sc-211139A sc-211139B | 1 mg 5 mg 10 mg | $357.00 $1234.00 $3198.00 | 1 | |
Cotinine N-β-D-Glucuronide is a metabolite of nicotine that exhibits intriguing interactions with acetylcholine receptors. Its glucuronidation enhances solubility and alters pharmacokinetics, impacting receptor affinity and signaling pathways. The compound's unique structural features enable it to modulate receptor activity through allosteric mechanisms, potentially influencing downstream cellular responses. Its presence in biological systems reflects complex metabolic processes and receptor regulation. | ||||||