Molecular structure of Anabasine hydrochloride, CAS Number: 15251-47-5
Anabasine hydrochloride (CAS 15251-47-5)
Application:
Anabasine hydrochloride is a potent nicotinic acetylcholine receptor agonist
CAS Number:
15251-47-5
Purity:
≥97%
Molecular Weight:
198.7
Molecular Formula:
C10H14N2•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Anabasine hydrochloride is a tobacco alkaloid and potent nicotinic AChR (acetylcholine receptor) agonist. Shown to inhibit the conversion of androstenedione of estrogen in human choriocarcinoma cells, via inhibiting the aromatase enzyme. In vitro, Anabasine hydrochloride may act to stimulate Ca2+-dependent catecholamine release from rat adrenomedullary cells.
Anabasine hydrochloride (CAS 15251-47-5) References
- Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy. | Jacob, P., et al. 2002. Cancer Epidemiol Biomarkers Prev. 11: 1668-73. PMID: 12496059
- Anabasine, a selective nicotinic acetylcholine receptor agonist, antagonizes MK-801-elicited mouse popping behavior, an animal model of schizophrenia. | Mastropaolo, J., et al. 2004. Behav Brain Res. 153: 419-22. PMID: 15265637
- Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry. | Xu, X., et al. 2004. Clin Chem. 50: 2323-30. PMID: 15472033
- Effect of anabasine on catecholamine secretion from the perfused rat adrenal medulla. | Hong, SP., et al. 2007. J Cardiol. 50: 351-62. PMID: 18186309
- Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro. | Barbieri, RL., et al. 1986. J Clin Invest. 77: 1727-33. PMID: 3711333
- Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors. | Kem, WR., et al. 1997. J Pharmacol Exp Ther. 283: 979-92. PMID: 9399967
Activator of:
AChR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Anabasine hydrochloride, 25 mg | sc-202053 | 25 mg | $20.00 | |||
Anabasine hydrochloride, 100 mg | sc-202053A | 100 mg | $41.00 |