Molecular structure of Decamethonium bromide, CAS Number: 541-22-0
Decamethonium bromide (CAS 541-22-0)
Alternate Names:
Decacuran; Syncurine
Application:
Decamethonium bromide is a nicotinic acetylcholine receptor partial agonist
CAS Number:
541-22-0
Purity:
≥98%
Molecular Weight:
418.29
Molecular Formula:
C16H38Br2N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
Decamethonium bromide is the dibromide salt of decamethonium, a depolarizing muscle relaxant which is used clinically in anesthesia. Decamethonium acts as a partial agonist of the AChR (nicotinic acetylcholine receptor).
Decamethonium bromide (CAS 541-22-0) References
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- PHARMACOLOGICAL STUDIES OF HEXAMETHYLENE-BIS-CARBAMINOYLCHOLINE (IMBRETIL) ON THE CARDIOVASCULAR AND RESPIRATORY SYSTEMS IN DOGS. | SAITO, S. and AVIADO, DM. 1963. Jpn Circ J. 27: 791-6. PMID: 14072887
- Short-term rigid and flaccid paralyses diminish growth of embryonic chick limbs and abrogate joint cavity formation but differentially preserve pre-cavitated joints. | Osborne, AC., et al. 2002. J Musculoskelet Neuronal Interact. 2: 448-56. PMID: 15758413
- Mechanobiology of embryonic skeletal development: Insights from animal models. | Nowlan, NC., et al. 2010. Birth Defects Res C Embryo Today. 90: 203-13. PMID: 20860060
- Ligand binding to nicotinic acetylcholine receptor investigated by surface plasmon resonance. | Kröger, D., et al. 1999. Anal Chem. 71: 3157-65. PMID: 21662906
- Role of paraventricular nucleus (PVH) in baroreflex-mediated changes in lumbar sympathetic nerve activity and heart rate. | Patel, KP. and Schmid, PG. 1988. J Auton Nerv Syst. 22: 211-9. PMID: 3418014
- Cardiovascular and respiratory responses evoked from the posterior cerebellar cortex and fastigial nucleus in the cat. | Bradley, DJ., et al. 1987. J Physiol. 393: 107-21. PMID: 3446792
- The effect of selected neuromuscular blocking agents and spinal cord transection on cortical after-discharge duration in the cat. | Straw, RN. 1968. Electroencephalogr Clin Neurophysiol. 25: 69-72. PMID: 4174785
- Regional vascular effects of vasopressin: plasma levels and circulatory responses. | Schmid, PG., et al. 1974. Am J Physiol. 227: 998-1004. PMID: 4440765
- Effect of bile salts on partitioning and oral toxicity of the bisquaternary ammonium drug decamethonium bromide. | Gaginella, TS., et al. 1974. J Pharm Sci. 63: 790-2. PMID: 4830006
- The effect of vagal stimulation and eserine on isolated guinea-pig oesophagus. | Bartlet, AL. 1968. Q J Exp Physiol Cogn Med Sci. 53: 170-4. PMID: 5185568
- Capillary electrophoresis analysis of chemical warfare agent breakdown products. I. Counterelectroosmotic separation of alkylphosphonic acids and their monoester derivatives. | Mercier, JP., et al. 1996. J Chromatogr A. 741: 279-85. PMID: 8785005
- Muscle and tendon size relationships in a paralyzed chick embryo model of clubfoot. | Germiller, JA., et al. 1998. J Pediatr Orthop. 18: 314-8. PMID: 9600555
Inhibitor of:
CHT1.Activator of:
AChR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Decamethonium bromide, 5 g | sc-239651 | 5 g | $122.00 |