MYH4 Activators
Common MYH4 Activators include, but are not limited to Cyclosporin A CAS 59865-13-3, L-3,3′,5-Triiodothyronine, free acid CAS 6893-02-3, Dexamethasone CAS 50-02-2, Ionomycin free acid CAS 56092-81-0 and Trichostatin A CAS 58880-19-6.
Myosin Heavy Chain 4 (MYH4) Activators define a distinct subgroup of chemical compounds known for their capacity to modulate the activity of the MYH4 gene. MYH4, also termed myosin heavy chain 4, encodes a vital protein within the myosin superfamily, playing a pivotal role in muscle contraction and motor protein functionality. Particularly pertinent to skeletal muscle development and operational dynamics, MYH4 activators refer to compounds that exhibit the distinctive ability to influence MYH4 gene expression or protein activity. Presumably, these compounds engage with regulatory components or molecular pathways linked to MYH4, resulting in augmented gene expression or altered protein function. The ramifications of MYH4 activators extend to muscle physiology, cellular processes, and developmental trajectories intrinsic to skeletal muscle tissue.
The exploration of MYH4 activators holds the promise of deepening our understanding of the molecular mechanisms underpinning muscle biology, unraveling insights that reverberate across various physiological processes. By elucidating the intricate interactions within the MYH4 gene and its protein product, these compounds may contribute to a more comprehensive comprehension of muscle-related physiological phenomena, extending their influence beyond the confines of a single gene expression event.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a β-adrenergic receptor agonist that activates cAMP signaling pathways, which can lead to the activation of transcription factors influencing Myh4 expression in skeletal muscle cells. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporin A is an immunosuppressive suggested compound that can activate calcineurin, a phosphatase involved in the calcineurin/NFAT pathway. This pathway can impact Myh4 expression, particularly in slow-twitch muscle fibers. | ||||||
L-3,3′,5-Triiodothyronine, free acid | 6893-02-3 | sc-204035 sc-204035A sc-204035B | 10 mg 100 mg 250 mg | $41.00 $77.00 $153.00 | ||
Triiodothyronine (T3) is a thyroid hormone that can influence muscle fiber type and Myh4 expression, promoting a shift toward fast-twitch characteristics. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a synthetic glucocorticoid that can modulate gene expression, potentially impacting Myh4 expression and muscle phenotype. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore that elevates intracellular calcium levels, potentially impacting Myh4 expression through calcium-dependent signaling pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is an HDAC inhibitor that affects chromatin structure and transcription factor accessibility, potentially influencing Myh4 expression. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone is a ligand for peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor that can modulate Myh4 expression and muscle phenotype. | ||||||