KLK6 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
Cysteine protease inhibitor; its inhibitory effect indirectly limits the availability of substrates for KLK. E-64 is an irreversible inhibitor that targets cysteine proteases by binding covalently to the active site. While it is specific for cysteine proteases, its effect on the broader protease network can influence KLK function indirectly. | ||||||
Nafamostat mesylate | 82956-11-4 | sc-201307 sc-201307A | 10 mg 50 mg | $82.00 $306.00 | 4 | |
Targets serine proteases, including KLK, by forming inhibitory complexes that suppress their catalytic function. Nafamostat is a broad-spectrum serine protease inhibitor that can influence a range of proteases. By modifying serine protease activity, it could affect KLK′s function indirectly through systemic protease inhibition. | ||||||
Tranexamic acid | 1197-18-8 | sc-204921 sc-204921A | 5 g 10 g | $29.00 $50.00 | 10 | |
Modulates the plasminogen activation system, indirectly affecting the cleavage and activation of substrates by KLK. | ||||||
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $65.00 $122.00 $428.00 $851.00 $1873.00 $4994.00 | 33 | |
AEBSF is a serine protease inhibitor that irreversibly binds to the active site of serine residues in proteases, thereby preventing the cleavage of peptide bonds by these enzymes. It can affect KLK′s activity by inhibiting its proteolytic function. | ||||||
Aprotinin | 9087-70-1 | sc-3595 sc-3595A sc-3595B | 10 mg 100 mg 1 g | $112.00 $408.00 $3000.00 | 51 | |
Aprotinin is a polypeptide that inhibits several serine proteases, including kallikreins. By inhibiting related proteases, aprotinin can modify the proteolytic environment and indirectly influence KLK activity. A proteinase inhibitor that can inhibit several serine proteases, including kallikreins | ||||||
Gabexate mesylate | 56974-61-9 | sc-215066 | 5 mg | $100.00 | ||
This is a synthetic serine protease inhibitor that can modulate the activity of multiple enzymes in the coagulation cascade. Through its broad-spectrum inhibition, it may have an effect on KLK′s role in processes related to coagulation and inflammation. Synthetic serine protease inhibitor that can inhibit KLK directly by interfering with its active site. | ||||||
Camostat mesylate | 59721-29-8 | sc-203867 sc-203867A sc-203867B sc-203867C sc-203867D sc-203867E | 10 mg 50 mg 500 mg 1 g 10 g 100 g | $43.00 $183.00 $312.00 $624.00 $2081.00 $4474.00 | 5 | |
Camostat is a serine protease inhibitor with actions on various proteases involved in the fibrinolytic system. It may affect KLK by altering the balance of serine proteases involved in skin desquamation and inflammation. | ||||||
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $168.00 $218.00 $404.00 $629.00 $4900.00 | 19 | |
Although primarily a matrix metalloproteinase inhibitor, marimastat′s inhibition of protease activity can influence the extracellular matrix and cellular processes that KLK might be involved in, thereby affecting its function. | ||||||
Chymostatin | 9076-44-2 | sc-202541 sc-202541A sc-202541B sc-202541C sc-202541D | 5 mg 10 mg 25 mg 50 mg 100 mg | $156.00 $260.00 $640.00 $1186.00 $2270.00 | 3 | |
Chymostatin is an inhibitor of chymotrypsin-like serine proteases. By inhibiting these proteases, it can impact related pathways and potentially alter the biological context in which KLK operates. | ||||||