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BML-287 is a selective inhibitor of Secreted Frizzled Related Protein-1 (FRP-1, EC50 = 6.97µM) useful for studying the Wnt signaling pathway.
1. Gopalsamy, Ariamala., et al., 2008. Identification of diarylsulfone sulfonamides as secreted frizzled related protein-1 (sFRP-1) inhibitors. Journal of medicinal chemistry. 51(24): 7670-2. PMID: 19053830
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