ABHD14B Activators refers to a class of chemical compounds specifically identified or designed to enhance the expression or activity of the ABHD14B enzyme, a member of the metabolic serine hydrolase family. These activators are characterized by their unique interaction with the ABHD14B enzyme, influencing its biochemical pathway. The primary function of these activators is to increase the catalytic efficiency or expression levels of ABHD14B. This is achieved through various molecular mechanisms, including altering the enzyme's conformation for optimal activity, facilitating the binding of substrates, or modulating the gene expression to increase the production of ABHD14B. The chemical nature of these activators can be diverse, ranging from small organic molecules to larger complex structures. Each activator is designed to interact specifically with the ABHD14B enzyme, often targeting unique sites on the enzyme to prevent off-target effects.
The development and study of ABHD14B Activators are rooted in a deep understanding of the enzyme's structure and function. ABHD14B, being a part of the broader serine hydrolase family, plays a role in diverse hydrolytic reactions involving compounds like lipids, esters, and amides. The activators are thus tailored to engage with this enzyme in a manner that maximizes its intrinsic activity. This engagement might involve stabilizing the active site conformation, protecting the enzyme from deactivation, or enhancing the enzyme's affinity for its natural substrates. The intricate design of these activators is based on detailed biochemical and biophysical studies, including enzyme kinetics, crystallography, and computational modeling. Through these studies, specific molecular interactions between the activators and ABHD14B are elucidated, guiding the refinement of these compounds for optimal interaction with the enzyme. The study of ABHD14B Activators, therefore, represents a sophisticated area of biochemistry and molecular biology, focusing on the precise modulation of a specific enzymatic function.
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| 製品名 | CAS # | カタログ # | 数量 | 価格 | 引用文献 | レーティング |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNAメチル化酵素阻害剤で、DNAの脱メチル化を引き起こし、ZNF544のようなジンクフィンガータンパク質をコードする遺伝子を含む遺伝子発現に影響を及ぼす可能性がある。 | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
クロマチン構造と遺伝子発現を変化させるHDAC阻害剤で、ZNF544の転写活性に影響を与える可能性がある。 | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
HDAC阻害剤でもあり、クロマチンリモデリングと遺伝子発現に影響を与え、ZNF544の転写調節活性に影響を与える可能性がある。 | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
レチノイン酸受容体を介して遺伝子発現に影響を与え、ZNF544を含む転写因子に影響を与える可能性がある。 | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
ビタミンD受容体を介して遺伝子発現を調節し、ZNF544のような転写因子の発現や機能に影響を与える可能性がある。 | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
様々な細胞内シグナル伝達経路に影響を及ぼし、ZNF544を含む転写因子や遺伝子制御に関与するタンパク質に影響を及ぼす可能性がある。 | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
ポリフェノールは遺伝子発現や細胞ストレス経路に影響を与え、転写制御に関与するZNF544のようなタンパク質に影響を与える可能性がある。 | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
サーチュイン活性と遺伝子発現に影響を与え、ZNF544を含む転写因子を調節する可能性がある。 | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
遺伝子発現と細胞の解毒経路に影響を与え、ZNF544のような転写因子に影響を与える可能性がある。 | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
チロシンキナーゼ阻害剤で、シグナル伝達経路と遺伝子発現を調節することができ、転写調節におけるZNF544の役割に影響を与える可能性がある。 | ||||||