ZNF544 Antibody (3359C4a): sc-81145

ZNF544 Antibody (3359C4a) is a mouse monoclonal IgG1 antibody that detects the ZNF544 protein of human origin by western blotting (WB) and immunoprecipitation (IP). Anti-ZNF544 antibody (3359C4a) is available as a non-conjugated format. ZNF544 (3359C4a) antibody recognizes a member of the Krüppel C2H2-type zinc-finger protein family, primarily located in the nucleus, where ZNF544 plays a crucial role in transcriptional regulation. This nuclear localization enables ZNF544 to interact directly with DNA and other nuclear proteins, influencing gene expression and cellular function. ZNF544 consists of 715 amino acids, featuring 13 C2H2-type zinc fingers and a KRAB domain, which is essential for interaction with the KAP1 protein. This interaction facilitates recruitment of histone-modifying enzymes, impacting chromatin remodeling and gene silencing. Understanding ZNF544′s function and localization helps elucidate its role in various biological processes and potential implications in diseases related to transcriptional dysregulation.

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ZNF544 Antibody (3359C4a) References:

1. The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor.  |  Sun, Y., et al. 2003. IUBMB Life. 55: 127-31. PMID: 12822888
2. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.  |  Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
3. A novel subfamily of zinc finger genes involved in embryonic development.  |  Nakamura, M., et al. 2004. J Cell Biochem. 93: 887-95. PMID: 15449319
4. A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE.  |  Li, Y., et al. 2006. Mol Biol Rep. 33: 287-94. PMID: 17089209
5. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.  |  O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
6. Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity.  |  Zhong, Z., et al. 2007. J Biochem Mol Biol. 40: 517-24. PMID: 17669267
7. [Comparative proteomics of the serum in patients with nasopharyngeal carcinoma: a study with two-dimensional electrophoresis and MALDI-TOF-MS].  |  Liao, QL., et al. 2008. Nan Fang Yi Ke Da Xue Xue Bao. 28: 154-8. PMID: 18250030
8. Epigenetic profiling of ADHD symptoms trajectories: a prospective, methylome-wide study.  |  Walton, E., et al. 2017. Mol Psychiatry. 22: 250-256. PMID: 27217153
9. Novel multilocus imprinting disturbances in a child with expressive language delay and intellectual disability.  |  Tayeh, MK., et al. 2022. Am J Med Genet A. 188: 2209-2216. PMID: 35365979
10. Identification of a novel circRNA-miRNA-mRNA regulatory axis in hepatocellular carcinoma based on bioinformatics analysis.  |  Zhong, G., et al. 2023. Sci Rep. 13: 3728. PMID: 36878930
11. The Way to Malignant Transformation: Can Epigenetic Alterations Be Used to Diagnose Early-Stage Head and Neck Cancer?  |  Lai, TY., et al. 2023. Biomedicines. 11: PMID: 37371812
12. A microdeletion event at 19q13.43 in IDH-mutant astrocytomas is strongly correlated with MYC overexpression.  |  Ülgen, E., et al. 2024. Acta Neuropathol Commun. 12: 95. PMID: 38877600

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF544 Antibody (3359C4a) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF544 Antibody (3359C4a) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF544 Antibody (3359C4a) Specifications

Alternate Product Name: ZNF544

Product Clone Name: 3359C4a

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: ZNF544

Epitope Species: human

Product Reactivity/Detection: ZNF544

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF544 Antibody (3359C4a): N/A