Reg IIIγ inhibitors belong to a class of chemical compounds designed to specifically target and modulate the activity of the Regenerating Islet-Derived 3 Gamma (Reg IIIγ) protein. This chemical class is primarily developed for research purposes, aiming to elucidate the role of Reg IIIγ in various biological processes. Reg IIIγ is a member of the Reg family of proteins, which are predominantly found in the gastrointestinal tract and play essential roles in regulating cell growth, inflammation, and tissue repair. Reg IIIγ, in particular, has been implicated in inflammatory responses, tissue damage, and certain pathological conditions.
The inhibitors within this chemical class are designed to interact with Reg IIIγ at the molecular level, disrupting its normal functions or inhibiting its expression. This disruption can be achieved through various mechanisms, such as blocking the binding sites of Reg IIIγ to its target molecules or interfering with the signaling pathways it participates in. Researchers use these inhibitors in laboratory settings to gain a deeper understanding of the protein's physiological functions and the implications of its dysregulation in various diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
JAK Inhibitor I | 457081-03-7 | sc-204021 sc-204021A | 500 µg 1 mg | $156.00 $339.00 | 59 | |
JAK/STAT signaling is a pathway that can be involved in the modulation of inflammation and can be related to the function of Reg IIIγ. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that may disrupt downstream signaling which could indirectly affect Reg IIIγ-related pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
This p38 MAP kinase inhibitor could alter inflammatory response pathways that may be associated with Reg IIIγ activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, which could impact the MAPK/ERK pathway and possibly the activity of proteins like Reg IIIγ. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor could modulate stress response pathways that might intersect with Reg IIIγ's role in cellular regeneration. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor that could affect pathways potentially related to Reg IIIγ's functions. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
MEK inhibitor that could also influence the MAPK/ERK pathway and indirectly affect Reg IIIγ-related activities. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that could affect protein degradation pathways, possibly impacting Reg IIIγ levels. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
NF-κB inhibitor that could modify inflammatory responses where Reg IIIγ might be involved. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
JAK2 inhibitor which might alter signaling pathways related to Reg IIIγ function. | ||||||