Date published: 2026-6-25

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Reg IIIγ Inhibitors

Reg IIIγ inhibitors belong to a class of chemical compounds designed to specifically target and modulate the activity of the Regenerating Islet-Derived 3 Gamma (Reg IIIγ) protein. This chemical class is primarily developed for research purposes, aiming to elucidate the role of Reg IIIγ in various biological processes. Reg IIIγ is a member of the Reg family of proteins, which are predominantly found in the gastrointestinal tract and play essential roles in regulating cell growth, inflammation, and tissue repair. Reg IIIγ, in particular, has been implicated in inflammatory responses, tissue damage, and certain pathological conditions.

The inhibitors within this chemical class are designed to interact with Reg IIIγ at the molecular level, disrupting its normal functions or inhibiting its expression. This disruption can be achieved through various mechanisms, such as blocking the binding sites of Reg IIIγ to its target molecules or interfering with the signaling pathways it participates in. Researchers use these inhibitors in laboratory settings to gain a deeper understanding of the protein's physiological functions and the implications of its dysregulation in various diseases.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

JAK Inhibitor I

457081-03-7sc-204021
sc-204021A
500 µg
1 mg
$156.00
$339.00
59
(1)

JAK/STAT signaling is a pathway that can be involved in the modulation of inflammation and can be related to the function of Reg IIIγ.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor that may disrupt downstream signaling which could indirectly affect Reg IIIγ-related pathways.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

This p38 MAP kinase inhibitor could alter inflammatory response pathways that may be associated with Reg IIIγ activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

An inhibitor of MEK, which could impact the MAPK/ERK pathway and possibly the activity of proteins like Reg IIIγ.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor could modulate stress response pathways that might intersect with Reg IIIγ's role in cellular regeneration.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor that could affect pathways potentially related to Reg IIIγ's functions.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

MEK inhibitor that could also influence the MAPK/ERK pathway and indirectly affect Reg IIIγ-related activities.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

A proteasome inhibitor that could affect protein degradation pathways, possibly impacting Reg IIIγ levels.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

NF-κB inhibitor that could modify inflammatory responses where Reg IIIγ might be involved.

Tyrphostin B42

133550-30-8sc-3556
5 mg
$26.00
4
(1)

JAK2 inhibitor which might alter signaling pathways related to Reg IIIγ function.