ZNF70, known as Zinc Finger Protein 70, is a member of the zinc finger protein family, which represents one of the largest families of transcription factors in eukaryotic organisms. These proteins are characterized by the presence of zinc finger motifs, which are small protein domains that stabilize a finger-like fold through coordination of one or more zinc ions. These motifs facilitate specific interactions with DNA, RNA, or other proteins, often through recognition and binding to specific sequences within the genome.
The precise biological functions of ZNF70 are not as well-characterized as some other members of the zinc finger protein family. However, based on the common functionalities of zinc finger proteins, ZNF70 is likely involved in transcriptional regulation, where it might bind to DNA and modulate the expression of target genes. The specific DNA-binding sequence recognized by ZNF70 would be determined by the amino acid residues present within its zinc finger domains, which dictate the protein's DNA-binding specificity.Like other zinc finger proteins, ZNF70 may play a role in various cellular processes, including cell growth, differentiation, and apoptosis, by regulating gene networks associated with these functions. Alterations in the expression or function of ZNF70 may have implications in developmental processes and could be associated with disease states, including cancer, where dysregulation of transcription factors often contributes to uncontrolled cell proliferation and survival.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor that can alter gene expression, potentially affecting the regulatory roles of ZNF70 in gene transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
TSA is a histone deacetylase inhibitor, affecting chromatin structure and gene expression, which may indirectly influence ZNF70 activity. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Disulfiram can bind to copper and possibly interfere with zinc homeostasis, potentially impacting zinc finger proteins like ZNF70. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Pyrithione Zinc can affect zinc metabolism and availability, potentially influencing the function of zinc-dependent proteins like ZNF70. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can modulate various signaling pathways, including those affecting transcription factors, possibly influencing ZNF70. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate various signaling pathways and affect gene expression, potentially influencing ZNF70 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK, part of the MAPK pathway, which can interact with transcription factors, potentially affecting ZNF70. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor; JNK pathway can modulate transcription factors, potentially influencing ZNF70. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride inhibits GSK-3β, a kinase that can regulate transcription factors. Inhibition of GSK-3β might indirectly influence ZNF70 activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a kinase that can influence transcription factor activity, possibly affecting ZNF70. |