Date published: 2025-11-24

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ZNF621 Inhibitors

Zinc finger protein 621 (ZNF621) is a member of the broad zinc finger protein family, characterized by the presence of zinc finger motifs which are fundamental for their role as transcription factors in eukaryotic cells. The defining feature of these proteins is their zinc finger domains, wherein zinc ions are coordinated with cysteine and/or histidine residues to create a stable, finger-like loop structure that can interact with DNA, RNA, or other proteins.ZNF621, like other zinc finger proteins, is presumed to be involved in DNA-binding and transcription regulation due to its zinc finger domains. These domains facilitate the specific recognition of DNA sequences, allowing ZNF621 to potentially control the transcription of genes by binding to their promoters or other regulatory regions.

The precise DNA sequences that ZNF621 recognizes, as well as the genes it regulates, are not comprehensively defined. However, based on the canonical roles of zinc finger proteins, ZNF621 is speculated to participate in a variety of cellular functions, which may include cellular differentiation, proliferation, apoptosis, and responses to external signals.The biological significance of ZNF621 lies in its potential regulatory influence on gene expression, which can shape cellular behavior and fate. Dysregulation of ZNF621 activity, due to mutations or aberrant expression, might have implications for disease development, especially if it affects genes involved in critical cellular pathways.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor, potentially affecting gene expression patterns and indirectly influencing ZNF621 activity.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

A histone deacetylase (HDAC) inhibitor, which may alter chromatin structure and gene expression, potentially impacting ZNF621.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Another HDAC inhibitor, potentially affecting gene regulation and indirectly influencing ZNF621 activity.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

A DNA methyltransferase inhibitor, which can alter gene expression and potentially impact ZNF621.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Similar to 5-Azacytidine, affects DNA methylation and gene expression, potentially influencing ZNF621.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

A selective HDAC inhibitor, which may have implications for gene regulation involving ZNF621.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$226.00
$846.00
1
(0)

A BET bromodomain inhibitor, potentially influencing gene expression and regulatory mechanisms involving ZNF621.

I-BET 151 Hydrochloride

1300031-49-5 (non HCl Salt)sc-391115
10 mg
$450.00
2
(0)

Another BET bromodomain inhibitor, which can affect transcription regulation, potentially impacting ZNF621.

A-366

1527503-11-2sc-507495
10 mg
$195.00
(0)

A G9a/GLP histone methyltransferase inhibitor, potentially altering epigenetic marks and gene expression relevant to ZNF621.

UNC1999

1431612-23-5sc-475314
5 mg
$142.00
1
(0)

A selective EZH2/EZH1 inhibitor, potentially affecting gene expression patterns relevant to ZNF621.