Zinc finger protein 621 (ZNF621) is a member of the broad zinc finger protein family, characterized by the presence of zinc finger motifs which are fundamental for their role as transcription factors in eukaryotic cells. The defining feature of these proteins is their zinc finger domains, wherein zinc ions are coordinated with cysteine and/or histidine residues to create a stable, finger-like loop structure that can interact with DNA, RNA, or other proteins.ZNF621, like other zinc finger proteins, is presumed to be involved in DNA-binding and transcription regulation due to its zinc finger domains. These domains facilitate the specific recognition of DNA sequences, allowing ZNF621 to potentially control the transcription of genes by binding to their promoters or other regulatory regions.
The precise DNA sequences that ZNF621 recognizes, as well as the genes it regulates, are not comprehensively defined. However, based on the canonical roles of zinc finger proteins, ZNF621 is speculated to participate in a variety of cellular functions, which may include cellular differentiation, proliferation, apoptosis, and responses to external signals.The biological significance of ZNF621 lies in its potential regulatory influence on gene expression, which can shape cellular behavior and fate. Dysregulation of ZNF621 activity, due to mutations or aberrant expression, might have implications for disease development, especially if it affects genes involved in critical cellular pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, potentially affecting gene expression patterns and indirectly influencing ZNF621 activity. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
A histone deacetylase (HDAC) inhibitor, which may alter chromatin structure and gene expression, potentially impacting ZNF621. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another HDAC inhibitor, potentially affecting gene regulation and indirectly influencing ZNF621 activity. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $128.00 $505.00 | 2 | |
A DNA methyltransferase inhibitor, which can alter gene expression and potentially impact ZNF621. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Similar to 5-Azacytidine, affects DNA methylation and gene expression, potentially influencing ZNF621. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
A selective HDAC inhibitor, which may have implications for gene regulation involving ZNF621. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
A BET bromodomain inhibitor, potentially influencing gene expression and regulatory mechanisms involving ZNF621. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
Another BET bromodomain inhibitor, which can affect transcription regulation, potentially impacting ZNF621. | ||||||
A-366 | 1527503-11-2 | sc-507495 | 10 mg | $195.00 | ||
A G9a/GLP histone methyltransferase inhibitor, potentially altering epigenetic marks and gene expression relevant to ZNF621. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
A selective EZH2/EZH1 inhibitor, potentially affecting gene expression patterns relevant to ZNF621. | ||||||