Date published: 2026-4-1

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ZNF618 Activators

The proposed chemical activators for ZNF618 function through various mechanisms that could impact zinc finger proteins' roles in transcriptional regulation and DNA binding. Compounds like 5-Azacytidine and Trichostatin A, which affect DNA methylation and histone acetylation, respectively, could alter the chromatin landscape, influencing ZNF618's ability to regulate gene expression. Similarly PD98059 and LY294002 might indirectly modulate the activity of transcription factors, including zinc finger proteins, by affecting key signaling pathways like MAPK/ERK and PI3K/AKT.

Additionally, compounds like Curcumin and Forskolin, which have broad effects on cellular signaling and transcriptional regulation, could also impact ZNF618's function. By modulating transcription factors and cellular signaling cascades, these compounds could indirectly influence the regulatory roles of zinc finger proteins like ZNF618. Moreover Bortezomib, Geldanamycin, and 17-AAG, might affect the stability and function of various transcription factors, which could include ZNF618.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

As a DNA methyltransferase inhibitor, 5-Azacytidine can alter gene expression patterns, potentially affecting the transcriptional regulatory functions of ZNF618.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A histone deacetylase inhibitor, Trichostatin A, can modify chromatin structure, potentially influencing ZNF618's role in gene regulation.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

As a MEK inhibitor, PD98059 may indirectly affect transcription factors including zinc finger proteins like ZNF618 in the MAPK/ERK pathway.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

This PI3K inhibitor could impact signaling pathways that indirectly involve transcriptional regulation, potentially influencing ZNF618’s activity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Known for its broad regulatory effects on transcription factors, curcumin could potentially influence ZNF618’s function in gene expression.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

As an activator of protein kinase C, PMA might indirectly influence ZNF618’s role in signal transduction pathways.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

By elevating cAMP levels, forskolin can modulate a range of cellular processes, possibly affecting ZNF618's function in transcriptional regulation.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor like rapamycin could impact ZNF618 indirectly by modulating pathways related to cell growth and transcriptional regulation.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

As a histone deacetylase inhibitor, it might affect chromatin remodeling and potentially influence ZNF618's transcriptional regulatory activities.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

This proteasome inhibitor can affect various cellular signaling pathways, potentially influencing ZNF618’s activity indirectly.