ZNF35, or Zinc Finger Protein 35, is part of the zinc finger protein family, which is characterized by its ability to bind DNA and influence the transcription of genes. These proteins play pivotal roles in various biological processes, including cell growth, repair, differentiation, and metabolism. ZNF35, in particular, is thought to be involved in transcriptional regulation, which is the process by which certain sections of DNA are activated or deactivated. The exact mechanisms and the full spectrum of genes that ZNF35 controls are not entirely understood, but it is recognized that the expression of ZNF35 itself can be sensitive to various biochemical signals. Understanding the regulation of ZNF35 is important for comprehending how genes are expressed in different cellular contexts and can provide insights into the fundamental workings of gene regulation networks.
Several chemical compounds have been identified that could potentially act as activators for the expression of ZNF35. These activators work through diverse pathways to either upregulate or stimulate the production of ZNF35. For example, certain compounds can alter the epigenetic markers on DNA, making the ZNF35 gene more accessible for transcription. Others may interact with intracellular signaling pathways, which can lead to the activation of transcription factors that target the ZNF35 gene. Additionally, some activators may interact directly with the gene's promoter regions, enhancing the recruitment of transcription machinery. It is important to note that these compounds can have wide-ranging actions and may influence the expression of multiple genes, not solely ZNF35. The intricate nature of gene expression regulation necessitates detailed research to elucidate the precise effects of these activators on ZNF35 expression and to understand their role within the cellular environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can initiate cellular differentiation and proliferation processes that may upregulate the transcription of zinc finger proteins, including ZNF35, by altering transcription factor binding. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound can reactivate epigenetically silenced genes by inhibiting DNA methyltransferase, potentially leading to an increase in ZNF35 expression as part of the genomic response. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Epigallocatechin Gallate, a polyphenol in green tea, may stimulate the expression of certain genes through antioxidant mechanisms or by inhibition of DNA methyltransferases, which could include upregulation of ZNF35. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
The active form of Cholecalciferol can bind to its receptor and initiate transcriptional programs, which may stimulate the expression of ZNF35 through vitamin D response elements in gene promoters. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This compound can induce histone hyperacetylation, leading to an open chromatin state and an increase in gene transcription, which may include the upregulation of ZNF35. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate can lead to hyperacetylation of histones, promoting a transcriptionally active chromatin state that could include the stimulation of ZNF35 transcription. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can activate transcription factors and gene expression pathways, potentially stimulating ZNF35 expression through alterations in signal transduction. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP levels, which can lead to the activation of cAMP response element-binding protein (CREB) and an increase in transcription of target genes like ZNF35. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
This synthetic glucocorticoid can initiate transactivation or transrepression of glucocorticoid response element (GRE)-bearing genes, which may lead to enhanced transcription of ZNF35. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA can activate protein kinase C, which may lead to transcriptional activation of immediate-early genes, possibly resulting in the upregulation of ZNF35 expression. | ||||||