ZNF35 Antibody (C-11): sc-376972
- ZNF35 Antibody (C-11) is a mouse monoclonal IgG1 κ ZNF35 antibody provided at 200 µg/ml
- raised against amino acids 21-220 mapping near the N-terminus of ZNF35 of human origin
- ZNF35 Antibody (C-11) is recommended for detection of ZNF35 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ZNF35 Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-376972 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZNF35 Antibody (C-11) for WB and IHC(P) applications. These reagents are now offered in bundles with ZNF35 Antibody (C-11) (see ordering information below).
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SEE ALSO...
ZNF35 Antibody (C-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF35 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-ZNF35 antibody (C-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF35, also known as HF.10 or Zfp105, is a member of the Krüppel C2H2-type zinc finger protein family and is primarily localized in the nucleus, where ZNF35 plays a crucial role in transcriptional regulation, cell differentiation, and proliferation. Notably, ZNF35 contains 11 C2H2-type zinc fingers, which are essential for DNA-binding capabilities, allowing ZNF35 to interact with specific gene promoters and modulate their expression. The gene encoding ZNF35 is located on chromosome 3, a region frequently implicated in deletions and rearrangements associated with various tumors, including renal and lung carcinoma. Additionally, the mouse homolog Zfp105 exhibits high expression levels in the testis, particularly in round spermatids and pachytene spermatocytes, highlighting ZNF35′s potential significance in reproductive biology. With versatile applications and critical role in gene regulation, ZNF35 (C-11) antibody is an invaluable tool for researchers studying the molecular mechanisms underlying cellular processes and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF35 Antibody (C-11) References:
- Structural and functional organization of the HF.10 human zinc finger gene (ZNF35) located on chromosome 3p21-p22. | Lanfrancone, L., et al. 1992. Genomics. 12: 720-8. PMID: 1572646
- Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. | O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
- Identification of a novel human zinc finger gene, ZNF438, with transcription inhibition activity. | Zhong, Z., et al. 2007. J Biochem Mol Biol. 40: 517-24. PMID: 17669267
- Localization of the human HF.10 finger gene on a chromosome region (3p21-22) frequently deleted in human cancers. | Donti, E., et al. 1990. Hum Genet. 84: 391-5. PMID: 2108922
- Deletion mapping of chromosome 3p in human uterine cervical cancer. | Kohno, T., et al. 1993. Oncogene. 8: 1825-32. PMID: 8099726
- YAC-assisted cloning of transcribed sequences from the human chromosome 3p21 region. | Pengue, G., et al. 1993. Hum Mol Genet. 2: 791-6. PMID: 8353497
- The ZNF35 human zinc finger gene encodes a sequence-specific DNA-binding protein. | Pengue, G., et al. 1993. FEBS Lett. 321: 233-6. PMID: 8477855
- Differential expression of the zinc finger gene Zfp105 during spermatogenesis. | Przyborski, SA., et al. 1998. Mamm Genome. 9: 758-62. PMID: 9716663
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF35 Antibody (C-11) | sc-376972 | 200 µg/ml | $316.00 | |||
ZNF35 Antibody (C-11): m-IgG Fc BP-HRP Bundle | sc-527562 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF35 Antibody (C-11): m-IgG1 BP-HRP Bundle | sc-532935 | 200 µg Ab; 20 µg BP | $354.00 | |||
ZNF35 Antibody (C-11) X | sc-376972 X | 200 µg/0.1 ml | $316.00 | |||
ZNF35 Antibody (C-11) AC | sc-376972 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZNF35 Antibody (C-11) HRP | sc-376972 HRP | 200 µg/ml | $316.00 | |||
ZNF35 Antibody (C-11) FITC | sc-376972 FITC | 200 µg/ml | $330.00 | |||
ZNF35 Antibody (C-11) PE | sc-376972 PE | 200 µg/ml | $343.00 | |||
ZNF35 Antibody (C-11) Alexa Fluor® 488 | sc-376972 AF488 | 200 µg/ml | $357.00 | |||
ZNF35 Antibody (C-11) Alexa Fluor® 546 | sc-376972 AF546 | 200 µg/ml | $357.00 | |||
ZNF35 Antibody (C-11) Alexa Fluor® 594 | sc-376972 AF594 | 200 µg/ml | $357.00 | |||
ZNF35 Antibody (C-11) Alexa Fluor® 647 | sc-376972 AF647 | 200 µg/ml | $357.00 | |||
ZNF35 Antibody (C-11) Alexa Fluor® 680 | sc-376972 AF680 | 200 µg/ml | $357.00 | |||
ZNF35 Antibody (C-11) Alexa Fluor® 790 | sc-376972 AF790 | 200 µg/ml | $357.00 |