ZMYND15 Inhibitors
ZMYND15 inhibitors encompasses a diverse set of chemical entities including histone deacetylase inhibitors like Trichostatin A and SAHA, which can impact chromatin structure and gene expression, potentially altering the functional role of ZMYND15 in the regulatory network of gene transcription. The inclusion of DNA methyltransferase inhibitors like 5-Azacytidine suggests an impact on epigenetic marks that can dictate the accessibility of ZMYND15 to its genomic targets. Proteasome inhibitors such as MG132 and Bortezomib are chosen based on the premise that they can stabilize or destabilize protein interactions within the cellular milieu, which in turn can modulate the activity of ZMYND15 indirectly by altering the abundance of regulatory proteins.
Kinase inhibitors like Genistein, Staurosporine, LY294002, KN-93, PD98059, and SP600125 are incorporated into this group based on their ability to modulate cellular signaling pathways, such as tyrosine kinase pathways, PI3K/Akt pathways, MAPK/ERK pathways, and JNK pathways. The diverse action of these inhibitors reflects the complexity of cellular signaling networks and highlights the broad strategy required to indirectly influence the activity of proteins like ZMYND15.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can remodel chromatin and influence gene expression, potentially affecting ZMYND15's role if it involves chromatin modulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can alter DNA methylation and gene expression, potentially impacting ZMYND15's regulatory functions. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can affect the degradation of proteins, potentially stabilizing ZMYND15's target proteins and thus modulating its activity. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Another histone deacetylase inhibitor which can lead to changes in gene expression that might be regulated by ZMYND15. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A tyrosine kinase inhibitor that can affect various signaling pathways, possibly interacting with pathways regulated by ZMYND15. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that can modulate a wide range of cell signaling pathways, potentially including those associated with ZMYND15. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor which could affect signaling pathways that ZMYND15 might be involved in, such as apoptosis or cell cycle regulation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that could influence the stability of proteins interacting with ZMYND15, altering its functional dynamics. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
A topoisomerase II inhibitor which can interfere with DNA replication and repair, potentially affecting ZMYND15's role in chromatin organization. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
An inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII), which might affect signaling pathways involving ZMYND15. | ||||||