ZC3H11A Activators
ZC3H11A activators are chemicals that indirectly modulate the activity or expression of ZC3H11A through their impact on cellular stress response pathways, mRNA stability, and zinc finger domain functionality. Since ZC3H11A is a zinc finger protein that plays a role in RNA metabolism under stress conditions, compounds that influence zinc availability, stress response elements, or mRNA processing can indirectly affect its activity.
The stress response in cells is a complex network of pathways that respond to various stimuli, including oxidative, ER, and heat shock stress. Compounds like Sodium Arsenite, Tunicamycin, and Thapsigargin are known to induce different types of stress responses, thereby modulating the role of ZC3H11A in these pathways. The stability and function of ZC3H11A are likely dependent on the proper zinc ion coordination in its zinc finger domains, making zinc availability crucial for its activity. Zinc Sulfate, by supplying zinc, can thus influence the structural and functional integrity of ZC3H11A.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is crucial for the structural integrity of zinc finger proteins. Zinc sulfate can enhance the structural stability of ZC3H11A, potentially affecting its RNA binding capability. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to GC-rich DNA sequences, potentially influencing the transcription of genes involved in stress response pathways that include ZC3H11A. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin modulates various signaling pathways, including those involved in cellular stress responses, which could indirectly affect ZC3H11A's role in RNA metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol affects numerous signaling pathways related to stress response and may indirectly influence ZC3H11A activity. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $106.00 $765.00 | 3 | |
Sodium arsenite induces oxidative stress, which could affect stress response pathways involving ZC3H11A. | ||||||
Heat Shock Protein Inhibitor I | 218924-25-5 | sc-221709 | 5 mg | $95.00 | 5 | |
Inhibitors of heat shock proteins can modulate stress response mechanisms, potentially impacting ZC3H11A activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor can alter gene expression patterns, potentially affecting ZC3H11A expression or related stress response pathways. | ||||||
Salubrinal | 405060-95-9 | sc-202332 sc-202332A | 1 mg 5 mg | $33.00 $102.00 | 87 | |
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and can influence the stress response, potentially affecting ZC3H11A activity. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin induces ER stress, which could modulate cellular stress response pathways involving ZC3H11A. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a known inducer of ER stress, which could influence ZC3H11A's role in stress response pathways. | ||||||