Chemicals classified as ZBTB38 activators encompass a diverse array of molecules that can indirectly influence the activity of ZBTB38 by modulating pathways and processes related to gene transcription regulation. Transcriptional regulation, the direct target of ZBTB38's activity, is tightly regulated by numerous factors including the methylation status of DNA, the acetylation status of histones, and the activity of protein complexes involved in gene silencing.
Some chemicals such as 5-Azacytidine can potentially modulate the activity of ZBTB38 by affecting the methylation status of DNA. Others, namely Trichostatin A, Vorinostat, Romidepsin, and Entinostat, indirectly influence ZBTB38 activity by affecting the acetylation status of histones, a key element in the regulation of gene transcription. Lastly, molecules such as JQ1, I-BET762, PFI-1, EPZ-6438, GSK126, UNC1999, and EED226 can indirectly modulate the activity of ZBTB38 by inhibiting proteins that read or write histone modifications, thereby changing the overall dynamics of gene transcription regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor that can indirectly influence ZBTB38 by altering the methylation status of DNA, which can affect transcriptional regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a histone deacetylase (HDAC) inhibitor that can indirectly affect ZBTB38 by changing the acetylation status of histones, a key element in the regulation of gene transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat is an HDAC inhibitor that can indirectly affect ZBTB38 by changing the acetylation status of histones. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
Romidepsin is an HDAC inhibitor that can indirectly affect ZBTB38 by changing the acetylation status of histones. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Entinostat is an HDAC inhibitor that can indirectly affect ZBTB38 by changing the acetylation status of histones. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 is a BET bromodomain inhibitor that can indirectly modulate ZBTB38 activity by altering the recognition of acetylated histones by BET proteins, thereby influencing transcriptional regulation. | ||||||
GSK 525762A | 1260907-17-2 | sc-490339 sc-490339A sc-490339B sc-490339C sc-490339D | 5 mg 10 mg 50 mg 100 mg 1 g | $300.00 $540.00 $940.00 $1680.00 $5900.00 | ||
I-BET762 is a BET bromodomain inhibitor that can indirectly modulate ZBTB38 activity by altering the recognition of acetylated histones by BET proteins. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $98.00 | ||
PFI-1 is a BET bromodomain inhibitor that can indirectly modulate ZBTB38 activity by altering the recognition of acetylated histones by BET proteins. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
EPZ-6438 is an inhibitor of EZH2, a component of the PRC2 complex that methylates histone H3, and can indirectly influence ZBTB38 by affecting this key element of gene transcription regulation. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $92.00 $243.00 $306.00 | ||
GSK126 is an EZH2 inhibitor and can indirectly influence ZBTB38 by affecting the methylation status of histone H3. | ||||||