ZBTB2 is a transcription factor that holds prominence in the orchestration of gene expression. To tap into its activation, certain biochemical agents have been identified. Forskolin, a well-known activator of adenylate cyclase, and cAMP analogs like 8-Bromoadenosine cAMP and Dibutyryl-cAMP can escalate cAMP levels, which further kindle protein kinase A (PKA). This action can lead to the modulation of transcriptional events, ushering in the potential upregulation of ZBTB2.
Furthermore, compounds like Anisomycin engage the JNK pathway, a cascade recognized for its role in dictating transcriptional dynamics. EGF, another pivotal molecule, can flag off pathways yielding transcriptional changes, thereby potentially amplifying ZBTB2 levels. On the other hand, PMA stimulates protein kinase C (PKC), another fulcrum in transcriptional regulation, and alongside IBMX, which elevates cAMP levels, these compounds can be pivotal for ZBTB2 activation.Calcium ionophores like Ionomycin and A23187 have also been acknowledged for their capacity to adjust transcriptional undertakings.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Adenylate cyclase activator that increases cAMP levels, potentially upregulating various transcription factors, possibly including ZBTB2. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
A cAMP analog that can activate PKA, influencing transcriptional events and possibly leading to ZBTB2 upregulation. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
An activator of Nrf2 pathway, potentially influencing downstream transcription factors like ZBTB2. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Activator of the JNK pathway, which can lead to the activation of various transcriptional responses potentially involving ZBTB2. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Another cAMP analog promoting PKA activation, potentially influencing ZBTB2. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PKC activator that can influence numerous transcriptional events, possibly impacting ZBTB2 expression. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Phosphodiesterase inhibitor, increasing cAMP levels, potentially leading to ZBTB2 upregulation. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $96.00 $334.00 | 50 | |
Activates multiple pathways influencing transcriptional responses, which could involve ZBTB2 upregulation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore that can influence various calcium-dependent signaling events, potentially impacting ZBTB2. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
Another calcium ionophore that may influence transcriptional responses leading to potential ZBTB2 upregulation. | ||||||