Date published: 2026-5-30

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VWC2 Inhibitors

The chemical class of VWC2 Inhibitors encompasses a range of compounds strategically designed to target and modulate the activity of VWC2, a protein characterized by the presence of the Von Willebrand factor C domain. This domain is notable for its involvement in key biological interactions, particularly in the organization of the extracellular matrix and in mediating essential protein-protein interactions. The primary focus of these inhibitors lies in their ability to influence these specific activities of VWC2, thereby providing a window into the protein's role in cellular physiology and pathology. The inhibitors in this class employ various methods to impact VWC2's function, taking advantage of the protein's structural and functional characteristics to achieve targeted modulation.

The mode of action of VWC2 inhibitors is diverse and multifaceted, reflecting the complex nature of the protein's involvement in various cellular processes. One approach targets the protein-protein interaction capabilities of VWC2, aiming to disrupt its ability to engage with other proteins, a function critical for its role in cellular signaling and structural organization. This disruption is key to understanding the broader implications of VWC2 in cellular communication and tissue integrity. Another critical method employed by these inhibitors is the modulation of extracellular matrix interactions, where compounds are designed to affect the protein's role in matrix assembly or remodeling. This is particularly significant given the extracellular matrix's role in tissue structure and function. Additionally, some inhibitors focus on altering cell signaling mechanisms linked with VWC2, targeting specific pathways that are essential for cell communication and response to external stimuli. The study of VWC2 inhibitors represents a targeted approach to probe the functions of a protein involved in crucial biological interactions. By modulating the activity of VWC2, these inhibitors provide unique insights into the protein's role in extracellular matrix organization, protein-protein interactions, and cellular signaling. The development of VWC2 inhibitors underscores the importance of understanding the nuanced roles of proteins like VWC2 in cellular processes and offers a strategic tool for dissecting these roles in greater detail. The research into VWC2 inhibitors is not just about inhibiting a protein's activity; it delves deeper into understanding the broader implications of key protein interactions in cellular health and disease. Through their targeted action on VWC2, these inhibitors contribute significantly to the field of biochemistry and molecular biology, emphasizing the potential of targeted molecular strategies in unraveling complex biological processes. They represent a crucial step in understanding the multifaceted roles of proteins like VWC2 in cellular function and regulation, providing valuable insights into the delicate balance of protein interactions within cells.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$53.00
$89.00
7
(1)

Might inhibit VWC2 by altering protein folding and stability, impacting its functional interactions.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Could inhibit VWC2 by directly impacting protein transport and secretion, affecting extracellular matrix processes.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Might inhibit VWC2 by disrupting glycoprotein synthesis, directly affecting protein-protein interactions.

Penicillamine

52-67-5sc-205795
sc-205795A
1 g
5 g
$46.00
$96.00
(0)

Might impact VWC2 by chelating metal ions and directly disrupting protein structure and function.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

Could inhibit VWC2 by directly impacting Ras signaling pathways, affecting cellular processes it's involved in.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Might inhibit VWC2 activity by targeting the PI3K/Akt pathway, directly involved in various cell functions.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Could modulate VWC2 function by inhibiting the p38 MAPK pathway, directly impacting signaling.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Might inhibit VWC2 by disrupting calcium homeostasis and signaling pathways directly.