VWA8 Inhibitors
VWA8 Inhibitors represent a collection of compounds that can indirectly modulate the function of the VWA8 protein. Given the roles associated with the Von Willebrand Factor A Domain, these inhibitors largely target processes related to cellular adhesion, migration, and protein-protein interactions. Compounds such as Batimastat, Marimastat, and GM6001, all matrix metalloproteinase (MMP) inhibitors, could influence the cellular adhesion processes that VWA8 may be associated with.
Another noteworthy approach to modulating VWA8 is by disrupting metal-dependent protein-protein interactions. Chelating agents such as EDTA and EGTA serve this purpose. The rationale here is that if VWA8's function is reliant on metal ions for its interactions, these agents can indirectly inhibit its activity. Furthermore, compounds like Suramin and Cilengitide, which act on growth factor receptors and integrins respectively, highlight the intricacy of cellular pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Batimastat | 130370-60-4 | sc-203833 sc-203833A | 1 mg 10 mg | $179.00 $377.00 | 24 | |
MMP inhibitor. Given the link between matrix metalloproteinases and cellular adhesion, inhibiting MMPs can potentially influence VWA8's role in this process. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $71.00 $288.00 | 6 | |
Inhibitor of endothelial cell proliferation. If VWA8 is involved in cell adhesion or migration, 2-ME can potentially modulate its role indirectly. | ||||||
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Non-selective antagonist of growth factor receptors. If VWA8 interacts with these receptors, Suramin can indirectly influence its function. | ||||||
Cilengitide | 188968-51-6 | sc-507335 | 5 mg | $215.00 | ||
Integrin antagonist. Integrins are involved in cell adhesion. If VWA8 operates within this pathway, Cilengitide can indirectly modulate its function. | ||||||
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $21.00 $65.00 $120.00 $251.00 $815.00 | 23 | |
Another chelating agent. Similar to EDTA, can disrupt metal-dependent interactions potentially linked to VWA8. | ||||||
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $168.00 $218.00 $404.00 $629.00 $4900.00 | 19 | |
Another MMP inhibitor, can modulate processes like cell adhesion if VWA8 is involved in them. | ||||||
GM 6001 | 142880-36-2 | sc-203979 sc-203979A | 1 mg 5 mg | $77.00 $270.00 | 55 | |
Broad-spectrum MMP inhibitor. Like other MMP inhibitors, can influence pathways VWA8 might be involved in, like cell adhesion. | ||||||
Cromolyn disodium salt | 15826-37-6 | sc-207459 sc-207459A sc-207459B sc-207459C sc-207459D sc-207459E sc-207459F | 1 g 5 g 25 g 50 g 100 g 500 g 1 kg | $50.00 $174.00 $624.00 $1040.00 $1873.00 $2913.00 $3537.00 | ||
Mast cell stabilizer. If VWA8 is linked with mast cell function or degranulation, this can indirectly modulate its function. | ||||||