Vmn1r165 Inhibitors would comprise a class of specialized chemical compounds designed to bind to and inhibit the Vmn1r165 receptor, if we are to assume that Vmn1r165 is a member of the vomeronasal type-1 receptor family involved in the detection of pheromonal signals. These inhibitors would function by preventing the interaction between the receptor and its natural ligands, hindering the receptor's ability to initiate the cellular response typically triggered by such an interaction. The inhibition could occur through direct competition with the ligand for binding sites on the receptor or by binding to alternative sites on the receptor to induce conformational changes that impede its function.
Creating Vmn1r165 inhibitors would involve a detailed investigation of the receptor's structure and the biochemistry of its interaction with ligands. This exploration would likely utilize techniques such as X-ray crystallography or cryo-electron microscopy to map the three-dimensional structure of the receptor, particularly focusing on the ligand-binding domain. Research into the function of Vmn1r165 and its interaction with potential inhibitors would provide deeper insights into the molecular mechanisms of chemosensory perception. By exploring how Vmn1r165 inhibitors affect the receptor's activity, scientists could better understand its role in the complex web of chemosensory signaling, including how it contributes to the detection of specific chemical cues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid might regulate gene expression by binding to retinoic acid receptors, which can bind to DNA and modulate transcription. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Raises intracellular cAMP levels, which could activate protein kinase A (PKA) and influence transcription factors that modulate gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
An HDAC inhibitor that may lead to a more open chromatin state, enhancing the accessibility of transcription machinery to DNA and potentially increasing gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This compound inhibits histone deacetylase, which could lead to altered histone acetylation, affecting chromatin structure and gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Can impact gene expression via estrogen receptors, which might bind to estrogen response elements on DNA and modulate transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Acts as a DNA methyltransferase inhibitor, potentially causing DNA demethylation and reactivation of silenced genes, thereby possibly increasing their expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Through glucocorticoid receptors, this compound may regulate gene expression by interacting with glucocorticoid response elements in the genome. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
May influence gene expression through modulation of epigenetic markers and signaling pathways, potentially affecting a wide array of genes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known to modulate transcription factors and signaling pathways, curcumin could potentially influence gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Affects gene expression by modulating sirtuin proteins and other signaling pathways, which could impact the transcription of various genes. | ||||||