VEGI Activators
VEGI Activators refers to a distinct class of chemical compounds characterized by their ability to modulate the expression and activity of Vascular Endothelial Growth Inhibitor (VEGI) proteins within biological systems. VEGI, also known as TNFSF15 (Tumor Necrosis Factor Ligand Superfamily member 15), is a cytokine that plays a pivotal role in regulating angiogenesis, the process by which new blood vessels are formed from existing ones. VEGI is particularly recognized for its anti-angiogenic properties, exerting inhibitory effects on the proliferation and migration of endothelial cells, which are crucial components in the formation of blood vessels.
VEGI Activators function by interacting with specific molecular pathways involved in the regulation of VEGI expression, ultimately influencing the downstream signaling cascades associated with angiogenesis. These chemical entities are designed to fine-tune the delicate balance between pro-angiogenic and anti-angiogenic factors, thereby exerting control over the intricate process of blood vessel development. The modulation of VEGI activity by these compounds holds promise in various biological contexts, particularly those related to pathological conditions characterized by aberrant angiogenesis. As research in this field progresses, a deeper understanding of the molecular mechanisms underlying VEGI activation and its consequences on angiogenic processes is expected to unravel.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenolic compound that can stimulate the sirtuin 1 (SIRT1) pathway, influencing the activity of many proteins, potentially including VEGI. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a natural polyphenolic compound that has been shown to modulate various signaling pathways, including NF-κB, which indirectly could influence VEGI activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that can modulate a wide range of kinases and enzymes, potentially influencing VEGI activity indirectly. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine can modulate a variety of cellular processes, potentially influencing VEGI activity indirectly. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin can stimulate TRPV1, which can indirectly influence VEGI activity. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Lycopene can modulate the activity of various signaling pathways, potentially influencing VEGI activity indirectly. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $52.00 $79.00 $104.00 $156.00 $2913.00 | 7 | |
Fisetin can modulate a variety of cellular processes and potentially influence VEGI activity indirectly. | ||||||
Pterostilbene, Pterocarpus marsupium | 537-42-8 | sc-203223 sc-203223A | 10 mg 100 mg | $211.00 $1196.00 | ||
Pterostilbene can modulate the activity of various signaling pathways, potentially influencing VEGI activity indirectly. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin is a flavonoid that can modulate a wide range of kinases and enzymes, potentially influencing VEGI activity indirectly. | ||||||