Date published: 2025-10-9

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UCP Antibodies

Santa Cruz Biotechnology features a diverse variety of UCP Antibodies for studying uncoupling proteins, which play a crucial role in regulating energy metabolism and thermogenesis in cells. UCP Antibodies support various research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Uncoupling proteins are integral to mitochondrial function, facilitating the dissipation of the proton gradient and thereby influencing ATP production and heat generation. Their regulation is vital for maintaining metabolic homeostasis and has implications in obesity, diabetes, and other metabolic disorders. Understanding uncoupling proteins can provide insights into essential physiological processes. Research applications include investigating mitochondrial energy transfer, cellular stress responses, and metabolic pathway regulation. Exploring uncoupling protein expression patterns helps reveal their role in different tissue types and physiological conditions. UCP research continues to uncover new connections between energy metabolism and various health conditions. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of energy metabolism and its impact on human health.

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UCP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

UCP1 Antibody (E-6)

sc-518171mouse IgG1 κ195-214 (h)WB, IP, IF, ELISAm, r, h
1
(1)

UCP1 Antibody (4E5)

sc-293418mouse IgG2a κ232-267 (h)WB, IP, ELISAm, r, h
24
(17)

UCP1 Antibody (A-6)

sc-518024mouse IgG2a κ284-307 (m)WB, IP, IF, IHC(P), ELISAm, r
7
(1)

UCP2 Antibody (G-6)

sc-390189mouse IgM κN-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h
32
(27)

UCP4 Antibody (A-5)

sc-365295mouse IgM κ17-37 (h)WB, IP, IF, IHC(P), ELISAm, r, h
4
(8)

UCP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

UCP1 CRISPR/Cas9 KO Plasmid (h)

sc-400410hGene KnockoutGFP0
(0)

UCP1 HDR Plasmid (h)

sc-400410-HDRhHomology Directed RepairPuromycin0
(0)

UCP1 Double Nickase Plasmid (h)

sc-400410-NIChGene KnockoutPuromycin0
(0)

UCP1 Double Nickase Plasmid (h2)

sc-400410-NIC-2hGene KnockoutPuromycin0
(0)

UCP1 CRISPR/Cas9 KO Plasmid (m)

sc-423595-KO-2mGene KnockoutGFP0
(0)

UCP1 HDR Plasmid (m2)

sc-423595-HDR-2mHomology Directed RepairPuromycin0
(0)

UCP1 Double Nickase Plasmid (m)

sc-423595-NICmGene KnockoutPuromycin0
(0)

UCP1 Double Nickase Plasmid (m2)

sc-423595-NIC-2mGene KnockoutPuromycin0
(0)

UCP2 CRISPR/Cas9 KO Plasmid (h)

sc-400319hGene KnockoutGFP0
(0)

UCP2 HDR Plasmid (h)

sc-400319-HDRhHomology Directed RepairPuromycin0
(0)

UCP2 Double Nickase Plasmid (h)

sc-400319-NIChGene KnockoutPuromycin0
(0)

UCP2 Double Nickase Plasmid (h2)

sc-400319-NIC-2hGene KnockoutPuromycin0
(0)

UCP2 CRISPR/Cas9 KO Plasmid (m)

sc-423596mGene KnockoutGFP0
(0)

UCP2 HDR Plasmid (m)

sc-423596-HDRmHomology Directed RepairPuromycin0
(0)

UCP2 Double Nickase Plasmid (m)

sc-423596-NICmGene KnockoutPuromycin0
(0)

UCP2 Double Nickase Plasmid (m2)

sc-423596-NIC-2mGene KnockoutPuromycin0
(0)

UCP3 CRISPR/Cas9 KO Plasmid (h)

sc-400866hGene KnockoutGFP0
(0)

UCP3 CRISPR/Cas9 KO Plasmid (h2)

sc-400866-KO-2hGene KnockoutGFP0
(0)

UCP3 HDR Plasmid (h2)

sc-400866-HDR-2hHomology Directed RepairPuromycin0
(0)

UCP3 Double Nickase Plasmid (h)

sc-400866-NIChGene KnockoutPuromycin0
(0)

UCP3 Double Nickase Plasmid (h2)

sc-400866-NIC-2hGene KnockoutPuromycin0
(0)

UCP3 CRISPR/Cas9 KO Plasmid (m)

sc-423597mGene KnockoutGFP0
(0)

UCP3 CRISPR/Cas9 KO Plasmid (m2)

sc-423597-KO-2m2Gene KnockoutGFP0
(0)

UCP3 HDR Plasmid (m2)

sc-423597-HDR-2m2Homology Directed RepairPuromycin0
(0)

UCP3 Double Nickase Plasmid (m)

sc-423597-NICmGene KnockoutPuromycin0
(0)

UCP3 Double Nickase Plasmid (m2)

sc-423597-NIC-2mGene KnockoutPuromycin0
(0)

UCP4 CRISPR/Cas9 KO Plasmid (h)

sc-417530hGene KnockoutGFP0
(0)

UCP4 HDR Plasmid (h)

sc-417530-HDRhHomology Directed RepairPuromycin0
(0)

UCP4 Double Nickase Plasmid (h)

sc-417530-NIChGene KnockoutPuromycin0
(0)

UCP4 Double Nickase Plasmid (h2)

sc-417530-NIC-2hGene KnockoutPuromycin0
(0)

UCP4 CRISPR/Cas9 KO Plasmid (m)

sc-428681mGene KnockoutGFP0
(0)

UCP4 HDR Plasmid (m)

sc-428681-HDRmHomology Directed RepairPuromycin0
(0)

UCP4 Double Nickase Plasmid (m)

sc-428681-NICmGene KnockoutPuromycin0
(0)

UCP4 Double Nickase Plasmid (m2)

sc-428681-NIC-2mGene KnockoutPuromycin0
(0)

UCP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

UCP1 CRISPR Activation Plasmid (h)

sc-400410-ACThGene ActivationPuro, Blast, Hygro0
(0)

UCP1 CRISPR Activation Plasmid (h2)

sc-400410-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP1 Lentiviral Activation Particles (h)

sc-400410-LAChGene ActivationPuro, Blast, Hygro0
(0)

UCP1 Lentiviral Activation Particles (h2)

sc-400410-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP1 CRISPR Activation Plasmid (m)

sc-423595-ACTmGene ActivationPuro, Blast, Hygro0
(0)

UCP1 CRISPR Activation Plasmid (m2)

sc-423595-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP1 Lentiviral Activation Particles (m)

sc-423595-LACmGene ActivationPuro, Blast, Hygro0
(0)

UCP1 Lentiviral Activation Particles (m2)

sc-423595-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP2 CRISPR Activation Plasmid (h)

sc-400319-ACThGene ActivationPuro, Blast, Hygro0
(0)

UCP2 CRISPR Activation Plasmid (h2)

sc-400319-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP2 Lentiviral Activation Particles (h)

sc-400319-LAChGene ActivationPuro, Blast, Hygro0
(0)

UCP2 Lentiviral Activation Particles (h2)

sc-400319-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP2 CRISPR Activation Plasmid (m)

sc-423596-ACTmGene ActivationPuro, Blast, Hygro0
(0)

UCP2 CRISPR Activation Plasmid (m2)

sc-423596-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP2 Lentiviral Activation Particles (m)

sc-423596-LACmGene ActivationPuro, Blast, Hygro0
(0)

UCP2 Lentiviral Activation Particles (m2)

sc-423596-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP3 CRISPR Activation Plasmid (h)

sc-400866-ACThGene ActivationPuro, Blast, Hygro0
(0)

UCP3 CRISPR Activation Plasmid (h2)

sc-400866-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP3 Lentiviral Activation Particles (h)

sc-400866-LAChGene ActivationPuro, Blast, Hygro0
(0)

UCP3 Lentiviral Activation Particles (h2)

sc-400866-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP3 CRISPR Activation Plasmid (m)

sc-423597-ACTmGene ActivationPuro, Blast, Hygro0
(0)

UCP3 CRISPR Activation Plasmid (m2)

sc-423597-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP3 Lentiviral Activation Particles (m)

sc-423597-LACmGene ActivationPuro, Blast, Hygro0
(0)

UCP3 Lentiviral Activation Particles (m2)

sc-423597-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP4 CRISPR Activation Plasmid (h)

sc-417530-ACThGene ActivationPuro, Blast, Hygro0
(0)

UCP4 CRISPR Activation Plasmid (h2)

sc-417530-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP4 Lentiviral Activation Particles (h)

sc-417530-LAChGene ActivationPuro, Blast, Hygro0
(0)

UCP4 Lentiviral Activation Particles (h2)

sc-417530-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

UCP4 CRISPR Activation Plasmid (m)

sc-428681-ACTmGene ActivationPuro, Blast, Hygro0
(0)

UCP4 CRISPR Activation Plasmid (m2)

sc-428681-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP4 Lentiviral Activation Particles (m)

sc-428681-LACmGene ActivationPuro, Blast, Hygro0
(0)

UCP4 Lentiviral Activation Particles (m2)

sc-428681-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

UCP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

UCP1 siRNA (h)

sc-42680hGene SilencingN/A0
(0)

UCP1 shRNA Plasmid (h)

sc-42680-SHhGene SilencingPuromycin0
(0)

UCP1 shRNA (h) Lentiviral Particles

sc-42680-VhGene SilencingPuromycin0
(0)

UCP1 siRNA (m)

sc-42681mGene SilencingN/A
1
(0)

UCP1 shRNA Plasmid (m)

sc-42681-SHmGene SilencingPuromycin
1
(0)

UCP1 shRNA (m) Lentiviral Particles

sc-42681-VmGene SilencingPuromycin
1
(0)

UCP2 siRNA (h)

sc-42682hGene SilencingN/A
10
(0)

UCP2 shRNA Plasmid (h)

sc-42682-SHhGene SilencingPuromycin
10
(0)

UCP2 shRNA (h) Lentiviral Particles

sc-42682-VhGene SilencingPuromycin
10
(0)

UCP2 siRNA (m)

sc-42683mGene SilencingN/A
2
(0)

UCP2 shRNA Plasmid (m)

sc-42683-SHmGene SilencingPuromycin
2
(0)

UCP2 shRNA (m) Lentiviral Particles

sc-42683-VmGene SilencingPuromycin
2
(0)

UCP2 siRNA (I. tridecemlineatus)

sc-270660I. tridecemlineatusGene SilencingN/A0
(0)

UCP2 shRNA Plasmid (I. tridecemlineatus)

sc-270660-SHI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP2 shRNA (I. tridecemlineatus) Lentiviral Particles

sc-270660-VI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP2 (I. tridecemlineatus)-PR

sc-270660-PRI. tridecemlineatusPrimerN/A0
(0)

UCP3 siRNA (h)

sc-42684hGene SilencingN/A0
(0)

UCP3 shRNA Plasmid (h)

sc-42684-SHhGene SilencingPuromycin0
(0)

UCP3 shRNA (h) Lentiviral Particles

sc-42684-VhGene SilencingPuromycin0
(0)

UCP3 siRNA (m)

sc-42685mGene SilencingN/A
1
(0)

UCP3 shRNA Plasmid (m)

sc-42685-SHmGene SilencingPuromycin
1
(0)

UCP3 shRNA (m) Lentiviral Particles

sc-42685-VmGene SilencingPuromycin
1
(0)

UCP4 siRNA (h)

sc-36775hGene SilencingN/A0
(0)

UCP4 shRNA Plasmid (h)

sc-36775-SHhGene SilencingPuromycin0
(0)

UCP4 shRNA (h) Lentiviral Particles

sc-36775-VhGene SilencingPuromycin0
(0)

UCP4 siRNA (m)

sc-36776mGene SilencingN/A0
(0)

UCP4 shRNA Plasmid (m)

sc-36776-SHmGene SilencingPuromycin0
(0)

UCP4 shRNA (m) Lentiviral Particles

sc-36776-VmGene SilencingPuromycin0
(0)

UCP4 siRNA (I. tridecemlineatus)

sc-270662I. tridecemlineatusGene SilencingN/A0
(0)

UCP4 shRNA Plasmid (I. tridecemlineatus)

sc-270662-SHI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP4 shRNA (I. tridecemlineatus) Lentiviral Particles

sc-270662-VI. tridecemlineatusGene SilencingPuromycin0
(0)

UCP4 (I. tridecemlineatus)-PR

sc-270662-PRI. tridecemlineatusPrimerN/A0
(0)