UBAP2 Inhibitors
UBAP2 inhibitors encompass a collection of chemicals that mainly impact the ubiquitin-proteasome system (UPS) or related cellular processes that UBAP2 might be involved in. The proteasome inhibitors, including MG-132, Lactacystin, Bortezomib, MLN2238, and Withaferin A, target the proteolytic activities of the proteasome. By impacting the UPS, these inhibitors can indirectly influence the functions of proteins like UBAP2 that are associated with ubiquitination processes. Additionally, there are chemicals like Eeyarestatin I and Spautin-1 that target other components of the UPS, such as the endoplasmic reticulum-associated protein degradation (ERAD) and ubiquitin-specific proteases, respectively. These agents further reinforce the to influence UBAP2's function within the UPS.
On the other hand, agents like Chloroquine, 3-Methyladenine, NH4Cl, and Concanamycin A influence lysosomal function or associated pathways. Given UBAP2's involvement in endosome-to-lysosome trafficking, these compounds might indirectly modulate the protein's functionality. In particular, Chloroquine and NH4Cl affect lysosomal acidification, which is a critical aspect of endosome-to-lysosome trafficking.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that can impact the UPS, indirectly influencing UBAP2's function associated with ubiquitination processes. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
Specific inhibitor of the proteasomal protease, potentially affecting the UPS and subsequently UBAP2 functionality. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitor, by impacting the UPS it can have an indirect influence on UBAP2. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Influences lysosomal function, potentially affecting endosome-to-lysosome trafficking processes related to UBAP2. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $65.00 $261.00 | 113 | |
Autophagy inhibitor which can influence lysosomal pathways, indirectly impacting processes related to UBAP2. | ||||||
Eeyarestatin I | 412960-54-4 | sc-358130B sc-358130 sc-358130A sc-358130C sc-358130D sc-358130E | 5 mg 10 mg 25 mg 50 mg 100 mg 500 mg | $114.00 $203.00 $354.00 $697.00 $1363.00 $5836.00 | 12 | |
Impairs endoplasmic reticulum-associated protein degradation (ERAD) which can indirectly affect UPS-related processes and UBAP2 function. | ||||||
Ixazomib | 1072833-77-2 | sc-489103 sc-489103A | 10 mg 50 mg | $311.00 $719.00 | ||
Proteasome inhibitor that, by influencing the UPS, can indirectly affect UBAP2 functionality. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
Acts on the proteasomal pathway, thereby can potentially influence the function of UBAP2. | ||||||
Spautin-1 | 1262888-28-7 | sc-507306 | 10 mg | $168.00 | ||
Inhibits specific ubiquitin-specific proteases, which can have indirect implications on UBAP2's role within the UPS. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $62.00 | 8 | ||
Lysosomotropic agent which can affect endosome-to-lysosome trafficking, potentially impacting UBAP2-associated processes. | ||||||