TYW3 Activators
TYW3 Activators constitute a specialized class of chemical compounds or molecules that have garnered interest within the domain of molecular biology and cellular research. These activators are designed or identified with the explicit purpose of modulating the activity of the TYW3 gene. TYW3, or Tyrosine tRNA Methyltransferase 3, is a protein-coding gene found in various organisms, including humans. It encodes an enzyme responsible for catalyzing the post-transcriptional modification of transfer RNA (tRNA), specifically involved in the addition of a methyl group to a specific tyrosine residue within tRNA molecules.
The investigation of TYW3 activators is intriguing because it allows researchers to delve into the precise role of the TYW3 gene in cellular physiology and molecular mechanisms associated with tRNA modification. Activation of TYW3 can offer valuable insights into its involvement in the complex process of tRNA maturation, ensuring the accuracy of protein synthesis within cells. By manipulating the activity of TYW3 through these activators, scientists aim to gain a deeper understanding of the intricate molecular pathways and cellular functions that rely on the gene product, thus contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, TYW3 activators serve as essential tools for researchers dedicated to unraveling the multifaceted molecular mechanisms that underlie cellular biology and the specific roles played by individual genes in these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $245.00 | 7 | |
As an mTOR inhibitor, it could alter protein synthesis pathways, potentially increasing the demand for modified tRNA and upregulating TYW3. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
By inhibiting protein synthesis, it might trigger compensatory mechanisms to enhance tRNA modification and TYW3 expression. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $166.00 $322.00 | 436 | |
Mimics aminoacyl-tRNAs, potentially disrupting normal translation and inducing TYW3 expression as a stress response. | ||||||
Sodium arsenite, 0.1N Standardized Solution | 7784-46-5 | sc-301816 | 500 ml | $130.00 | 4 | |
Induces oxidative stress, which could lead to upregulation of enzymes involved in tRNA modification like TYW3 for translational fidelity. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Causes DNA damage and replication stress, possibly enhancing the expression of TYW3 as part of the cellular response to maintain protein synthesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
As a modulator of SIRT1, it might influence TYW3 expression indirectly by affecting cellular stress pathways and metabolism. | ||||||
Salubrinal | 405060-95-9 | sc-202332 sc-202332A | 1 mg 5 mg | $34.00 $104.00 | 87 | |
Inhibits dephosphorylation of eIF2α, potentially upregulating TYW3 as part of the integrated stress response to ensure translational fidelity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Induces ER stress, potentially enhancing TYW3 expression as part of the unfolded protein response to maintain cellular function. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Triggers ER stress by inhibiting N-linked glycosylation, possibly upregulating TYW3 expression to cope with altered protein synthesis demand. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
Induces metabolic stress by inhibiting glycolysis, which might enhance TYW3 expression as part of the adaptive response to maintain energy balance. | ||||||