TTC38 Activators
TTC38 Activators are a group of chemical compounds that influence various cellular signaling cascades, resulting in the enhanced functional activity of TTC38. These activators operate through different biochemical mechanisms, with the common outcome of amplifying the activity or effects of TTC38 within the cell. While some of these activators work by increasing the levels of secondary messengers such as cAMP, which in turn can lead to the activation of protein kinases that phosphorylate TTC38, others may act by altering calcium signaling, which has downstream effects on kinases and phosphatases that modulate the activity of TTC38.
The activators include compounds that directly raise intracellular cAMP or calcium levels, indirectly influencing the activity of TTC38 by modulating the activity of kinases or calcium-binding proteins. Some activators are inhibitors of specific kinases or phosphatases, which can result in a compensatory response within the cell that leads to the activation of alternative pathways enhancing TTC38's activity. Others, like bioactive lipids, act through receptor-mediated signaling, potentially affecting TTC38's activity through kinase-linked pathways. These activators do not directly bind to TTC38; instead, they influence the cellular environment and signaling networks that control the functional state of TTC38, culminating in its enhanced activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A synthetic analog of cAMP that can permeate cell membranes and activate PKA. PKA can then phosphorylate TTC38 or associated regulatory proteins, enhancing TTC38's functional activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A calcium ionophore that raises intracellular calcium levels, which may activate calmodulin-dependent kinases, potentially leading to the phosphorylation and activation of TTC38 or its associated proteins. | ||||||
LY-333,531 Hydrochloride | 169939-93-9 | sc-364215 sc-364215A | 1 mg 5 mg | $94.00 $287.00 | 6 | |
A specific inhibitor of PKCβ, which may lead to compensatory actions in other PKC isoforms that can phosphorylate and enhance the activity of TTC38 or proteins within its signaling pathway. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
A bioactive lipid that acts as a ligand for S1P receptors, potentially causing downstream effects on kinases that may phosphorylate and enhance the activity of TTC38. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor, but at certain concentrations can paradoxically enhance tyrosine kinase activity, potentially affecting the phosphorylation state and activity of TTC38. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An adenylyl cyclase activator that increases intracellular cAMP levels, leading to the activation of PKA that can phosphorylate and enhance TTC38's functional activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
A calcium ionophore similar to A23187, it increases intracellular calcium and can activate signaling pathways that may lead to the phosphorylation and functional enhancement of TTC38. | ||||||
Calmidazolium chloride | 57265-65-3 | sc-201494 sc-201494A | 10 mg 50 mg | $156.00 $612.00 | 27 | |
A calmodulin antagonist that by inhibiting calmodulin, may lead to the activation of alternate pathways that compensate by enhancing TTC38's functional activity. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
A non-selective inhibitor of phosphodiesterase that prevents cAMP degradation, potentially enhancing PKA activity and subsequently phosphorylating and activating TTC38. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
A PKC inhibitor that can lead to alterations in PKC-mediated signaling pathways, potentially enhancing the functional activity of TTC38 through compensatory pathways. | ||||||