TTC38 Antibody (F-1): sc-514613
- TTC38 Antibody (F-1) is a mouse monoclonal IgG1 κ TTC38 antibody provided at 200 µg/ml
- raised against amino acids 112-396 mapping within an internal region of TTC38 of human origin
- TTC38 Antibody (F-1) is recommended for detection of TTC38 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TTC38 Antibody (F-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TTC38 Antibody (F-1) for WB applications. These reagents are now offered in bundles with TTC38 Antibody (F-1) (see ordering information below).
TTC38 Antibody (F-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects TTC38 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TTC38 Antibody (F-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TTC38 consists of 469 amino acids and features three tetratricopeptide repeat (TPR) motifs, playing a crucial role in mediating protein-protein interactions essential for various cellular pathways. TPR motifs, characterized by a degenerate 34 amino acid sequence, allow for the formation of helix-turn-helix structures that stack together, providing specificity in ligand binding. This structural arrangement is vital for TTC38′s function in cellular processes, including signal transduction and protein folding. TTC38 gene is located on chromosome 22, which houses over 500 genes and is implicated in several genetic disorders, including Phelan-McDermid syndrome and neurofibromatosis type 2. Understanding TTC38′s interactions and functions can provide insights into its role in health and disease, making anti-TTC38 antibody (F-1) an invaluable tool for researchers studying these complex biological systems.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TTC38 Antibody (F-1) References:
- [Chromosome 22q11 deletion syndrome and its relevance for child and adolescent psychiatry. An overview of etiology, physical symptoms, aspects of child development and psychiatric disorders]. | Briegel, W. and Cohen, M. 2004. Z Kinder Jugendpsychiatr Psychother. 32: 107-15. PMID: 15181786
- Genes, brain development and psychiatric phenotypes in velo-cardio-facial syndrome. | Gothelf, D., et al. 2008. Dev Disabil Res Rev. 14: 59-68. PMID: 18636637
- Association of the PIK4CA schizophrenia-susceptibility gene in adults with the 22q11.2 deletion syndrome. | Vorstman, JA., et al. 2009. Am J Med Genet B Neuropsychiatr Genet. 150B: 430-3. PMID: 18646052
- Array analysis and molecular studies of INI1 in an infant with deletion 22q13 (Phelan-McDermid syndrome) and atypical teratoid/rhabdoid tumor. | Sathyamoorthi, S., et al. 2009. Am J Med Genet A. 149A: 1067-9. PMID: 19334084
- Neurofibromatosis 2 [Bilateral acoustic neurofibromatosis, central neurofibromatosis, NF2, neurofibromatosis type II]. | Evans, DG. 2009. Genet Med. 11: 599-610. PMID: 19652604
- Molecular pathogenesis of Philadelphia-positive chronic myeloid leukemia - is it all BCR-ABL? | Rumpold, H. and Webersinke, G. 2011. Curr Cancer Drug Targets. 11: 3-19. PMID: 21062244
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TTC38 Antibody (F-1) | sc-514613 | 200 µg/ml | $322.00 | |||
TTC38 Antibody (F-1): m-IgG Fc BP-HRP Bundle | sc-527921 | 200 µg Ab; 10 µg BP | $361.00 | |||
TTC38 Antibody (F-1): m-IgG1 BP-HRP Bundle | sc-533294 | 200 µg Ab; 20 µg BP | $361.00 | |||
TTC38 Antibody (F-1) AC | sc-514613 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TTC38 Antibody (F-1) HRP | sc-514613 HRP | 200 µg/ml | $322.00 | |||
TTC38 Antibody (F-1) FITC | sc-514613 FITC | 200 µg/ml | $336.00 | |||
TTC38 Antibody (F-1) PE | sc-514613 PE | 200 µg/ml | $349.00 | |||
TTC38 Antibody (F-1) Alexa Fluor® 488 | sc-514613 AF488 | 200 µg/ml | $364.00 | |||
TTC38 Antibody (F-1) Alexa Fluor® 546 | sc-514613 AF546 | 200 µg/ml | $364.00 | |||
TTC38 Antibody (F-1) Alexa Fluor® 594 | sc-514613 AF594 | 200 µg/ml | $364.00 | |||
TTC38 Antibody (F-1) Alexa Fluor® 647 | sc-514613 AF647 | 200 µg/ml | $364.00 | |||
TTC38 Antibody (F-1) Alexa Fluor® 680 | sc-514613 AF680 | 200 µg/ml | $364.00 | |||
TTC38 Antibody (F-1) Alexa Fluor® 790 | sc-514613 AF790 | 200 µg/ml | $364.00 |