TTC17 Inhibitors
TTC17 inhibitors are chemicals that can modulate cellular pathways in which TTC17 or related proteins operate. Tetratricopeptide repeat (TPR) motifs are sequence-specific modules involved in protein-protein interactions. A number of the listed chemicals, such as Rapamycin, Cyclosporine, and FK506, exert their biological effects by interacting with proteins that contain TPR motifs. Their impact on signaling pathways underscores the intricate networks in which TPR-containing proteins like TTC17 might be involved.
HSP90 inhibitors, including Geldanamycin, 17-AAG, and Radicicol, target a heat shock protein whose co-chaperones often contain TPR motifs. Given this association, it's plausible that these inhibitors could indirectly influence TTC17 function or stability. The list also includes agents affecting cell proliferation, DNA/RNA synthesis, and protein degradation like Methotrexate, 5-Fluorouracil, Roscovitine, MG132, and Bortezomib. All these agents illustrate the broad cellular landscape and the crosstalk between TPR-containing proteins and various cellular pathways.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Affects mTOR signaling, potentially influencing proteins with TPR motifs or their associated pathways. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Immunosuppressant that can affect several TPR-containing proteins, potentially including TTC17. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $78.00 $151.00 | 9 | |
Another immunosuppressant that interacts with TPR motifs; could influence TTC17-associated pathways. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
HSP90 inhibitor; TPR motifs are found in co-chaperones of HSP90, indicating possible indirect effects on TTC17. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
An HSP90 inhibitor which could indirectly influence TPR-containing proteins or pathways involving TTC17. | ||||||
Radicicol | 12772-57-5 | sc-200620 sc-200620A | 1 mg 5 mg | $92.00 $333.00 | 13 | |
Another HSP90 inhibitor; TPR motifs are often part of HSP90 co-chaperones. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Affects cell proliferation and may impact the synthesis or function of TPR-containing proteins. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
Influences RNA and DNA synthesis which might indirectly affect TTC17 or associated processes. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
CDK inhibitor that impacts cell cycle and might influence TPR-containing proteins. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor that can impact degradation of proteins, including those with TPR motifs. | ||||||