TSSK 6 Activators
TSSK6, short for Testis-Specific Serine Kinase 6, is an enzyme encoded by the TSSK6 gene in humans. It belongs to the family of serine/threonine kinases, a group of enzymes that play critical roles in various cellular processes through the phosphorylation of serine or threonine residues in specific proteins. The TSSK family, including TSSK6, is predominantly expressed in testicular tissue, indicating a specialized role in testis function and spermatogenesis.TSSK6 is primarily involved in sperm development and maturation. It is active during the later stages of spermatogenesis, the process by which sperm cells are produced and matured. This kinase is believed to phosphorylate specific substrates involved in the structural and functional changes that sperm undergo during their development. These changes are essential for the acquisition of motility and the ability to fertilize an egg.
The precise molecular functions and targets of TSSK6 are still being elucidated, but its role in sperm maturation and function suggests its importance in male fertility. Mutations or dysregulation in the TSSK6 gene or its protein product may contribute to male infertility, characterized by defects in sperm motility or morphology.In addition to its role in spermatogenesis, there is ongoing research to explore functions of TSSK6 outside the testis. Like other kinases, it may be involved in broader cellular signaling pathways or processes in other tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which could indirectly influence TSSK 6 in spermatogenesis. | ||||||
H-89 dihydrochloride | 130964-39-5 | sc-3537 sc-3537A | 1 mg 10 mg | $94.00 $186.00 | 71 | |
H89 is a protein kinase A inhibitor, potentially affecting pathways where TSSK 6 is involved in testicular function. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX, a non-selective phosphodiesterase inhibitor, might indirectly affect TSSK 6 activity by altering sperm function. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
As a ROCK inhibitor, Y-27632 might indirectly modulate TSSK 6 activity through its effects on spermatogenesis and sperm motility. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
KN-93, a CaMKII inhibitor, may have an indirect influence on TSSK 6 activity in sperm development. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an MEK inhibitor, which could impact signaling pathways involving TSSK 6 in testicular cells. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125, a JNK inhibitor, might indirectly affect TSSK 6 activity by modulating spermatogenic signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, a PI3K inhibitor, could potentially influence TSSK 6 activity in testicular signaling pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, might indirectly impact TSSK 6 through its effects on sperm function and development. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $28.00 $79.00 $165.00 | 32 | |
Daidzein, an isoflavone, may indirectly affect TSSK 6 activity by influencing hormonal pathways in testicular function. | ||||||