TPD52 Inhibitors
TPD52 inhibitors belong to a class of chemical compounds designed to target and modulate the activity of TPD52, a protein associated with various cellular processes. TPD52, short for tumor protein D52, is a cytoplasmic protein that plays a role in intracellular trafficking, endocytosis, and signal transduction pathways. Inhibitors of TPD52 are molecular compounds designed to interfere with the normal function or expression of this protein, often through binding to specific regions or sites within the protein structure. By doing so, they can potentially disrupt cellular processes where TPD52 is involved.
The development of TPD52 inhibitors has garnered interest due to the protein's involvement in several cellular pathways. TPD52 has been implicated in processes such as cell division, membrane trafficking, and vesicle formation. Inhibition of TPD52 may affect these processes, offering insights into the fundamental mechanisms underlying cellular function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent, non-selective inhibitor of protein kinases which can inhibit TPD52 by interfering with its downstream signaling pathways that involve various kinases. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
Bisindolylmaleimide I, also known as GF109203X, is a specific inhibitor of protein kinase C (PKC) and can inhibit TPD52 by targeting the PKC-dependent pathways in which TPD52 may be involved. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a specific inhibitor of PI3K, which can inhibit TPD52 by disrupting the PI3K/AKT signaling pathway, likely affecting TPD52-mediated cellular processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a covalent inhibitor of phosphoinositide 3-kinases (PI3K), which can inhibit TPD52 by blocking the PI3K/AKT pathway, potentially influencing TPD52 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an inhibitor of mitogen-activated protein kinase kinase (MEK), which can inhibit TPD52 by affecting the MAPK/ERK pathway that may play a role in TPD52-related functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a non-competitive inhibitor of MEK, which can inhibit TPD52 by altering the MAPK/ERK signaling pathway, potentially affecting TPD52's role in this pathway. | ||||||
SB 202190 | 152121-30-7 | sc-202334 sc-202334A sc-202334B | 1 mg 5 mg 25 mg | $31.00 $128.00 $454.00 | 45 | |
SB203580 is a specific inhibitor of p38 MAP kinase, which can inhibit TPD52 by modulating the p38 MAPK signaling pathway that might be associated with TPD52 function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK), which can inhibit TPD52 by affecting the JNK signaling pathway that could be relevant to TPD52's activity. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Imatinib is a tyrosine kinase inhibitor that can inhibit TPD52 by targeting the tyrosine kinase-dependent pathways with which TPD52 may interact. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
Sorafenib is a multi-kinase inhibitor that can inhibit TPD52 by affecting various signaling pathways, including those related to angiogenesis and cell proliferation, where TPD52 may be involved. | ||||||