Date published: 2026-2-14

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Tom40B Activators

Tom40B activators represent a specialized class of chemical compounds that have garnered attention within the field of molecular biology and cellular processes. These compounds are meticulously designed to modulate the activity of Tom40B, a protein-coding gene with essential roles in cellular functions, particularly in the context of mitochondrial import and protein translocation. Tom40B, also known as Translocase of Outer Mitochondrial Membrane 40 Homolog B, is a component of the mitochondrial outer membrane, where it forms part of the protein translocase complex, facilitating the import of proteins into the mitochondria. Tom40B activators function by targeting specific regulatory elements within the Tom40B gene, often located in promoter or enhancer regions, with the primary aim of enhancing its transcription and subsequent translation into functional protein products.

The mechanisms through which Tom40B activators exert their effects may vary, but their central purpose is to act as molecular switches, amplifying the activity of Tom40B. Researchers are continually exploring the potential applications and implications of Tom40B activation, aiming to deepen our understanding of how this gene contributes to cellular processes, particularly within the context of mitochondrial protein import and the maintenance of mitochondrial function. This class of compounds holds promise for advancing our knowledge of mitochondrial biology, specifically focusing on the role of Tom40B in ensuring the proper import of proteins into this vital organelle, offering insights into the intricate mechanisms that govern mitochondrial homeostasis and cellular energy production. Tom40B activators serve as valuable tools in the ongoing exploration of molecular biology, providing opportunities to uncover the complex roles that Tom40B plays in cellular functions and its potential involvement in the intricate world of mitochondrial biology.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aminolevulinic Acid Hydrochloride Salt

5451-09-2sc-262399
sc-262399A
sc-262399B
sc-262399C
1 g
5 g
25 g
100 g
$41.00
$110.00
$320.00
$1400.00
2
(2)

This compound is a precursor in heme synthesis and might stimulate mitochondrial biogenesis, potentially increasing TOMM40 expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits mTOR, which could induce a cellular stress response that includes upregulation of mitochondrial proteins like TOMM40.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is known to activate sirtuins, which can lead to enhanced mitochondrial biogenesis and possibly TOMM40 expression.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

As a PPAR-γ agonist, pioglitazone has been shown to influence mitochondrial biogenesis, which may affect TOMM40 expression.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin activates AMPK which can lead to mitochondrial biogenesis, potentially impacting TOMM40 expression.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$57.00
$191.00
$302.00
$450.00
$1800.00
$3570.00
$10710.00
4
(2)

NAD+ is involved in redox reactions and its supplementation may enhance mitochondrial function and thus TOMM40 expression.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane can activate Nrf2, leading to a possible increase in mitochondrial biogenesis and TOMM40 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid can modulate gene expression, which might indirectly affect the expression of genes like TOMM40.

FCCP

370-86-5sc-203578
sc-203578A
10 mg
50 mg
$94.00
$355.00
46
(1)

FCCP uncouples oxidative phosphorylation, potentially increasing mitochondrial biogenesis and TOMM40 expression.

Mito-Q

444890-41-9sc-507441
5 mg
$290.00
(0)

MitoQ is targeted to mitochondria and could potentially enhance their biogenesis, impacting TOMM40 expression.