TMEM59 Inhibitors
TMEM59, or Transmembrane Protein 59, is a multifunctional protein located within the cell membrane, playing a role in various cellular processes. Its involvement in modulating the Wnt/β-catenin signaling pathway is noteworthy, a crucial pathway responsible for cellular proliferation, differentiation, and maintenance. TMEM59's interaction with components of the Wnt signaling pathway suggests its significant role in cellular development and homeostasis. Additionally, TMEM59 has been implicated in the regulation of cellular responses to different environmental stresses, thus contributing to the overall maintenance of cellular integrity and function.
Research has also hinted at TMEM59's involvement in the biology of cancer cells, given its role in essential signaling pathways. However, the full spectrum of TMEM59's function, interaction with other proteins, and involvement in various biological pathways remains a subject of ongoing research. A more detailed understanding of TMEM59's function and regulation will offer insight into its broader roles in cellular biology and its implications in various diseases, including cancer. The exploration of TMEM59 could unveil novel aspects of cellular signaling pathways and open new avenues for targeted strategies in disease contexts where TMEM59 is implicated.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
May demethylate DNA, potentially modifying the expression of TMEM59. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
Might inhibit p300, a histone acetyltransferase, possibly affecting TMEM59 expression. | ||||||
Chidamide | 743420-02-2 | sc-364462 sc-364462A sc-364462B | 1 mg 5 mg 25 mg | $61.00 $245.00 $1173.00 | ||
Could inhibit histone deacetylases, potentially modifying TMEM59 expression. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
Might inhibit gamma-secretase, possibly affecting pathways involving TMEM59. | ||||||
Epz004777 | 1338466-77-5 | sc-507560 | 100 mg | $575.00 | ||
May inhibit DOT1L methyltransferase, potentially affecting the expression of TMEM59. | ||||||
EX 527 | 49843-98-3 | sc-203044 | 5 mg | $85.00 | 32 | |
Could inhibit SIRT1, potentially affecting histone modification and TMEM59 expression. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $90.00 $238.00 $300.00 | ||
Might inhibit EZH2 methyltransferase, possibly affecting TMEM59 expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
May inhibit BET bromodomains, potentially affecting transcription of TMEM59. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Could inhibit the proteasome, potentially stabilizing proteins that regulate TMEM59. | ||||||
PF-3758309 | 898044-15-0 | sc-478493 | 10 mg | $260.00 | ||
Might inhibit PAK4, possibly affecting signaling pathways that regulate TMEM59. | ||||||