TMEM183A, standing for Transmembrane Protein 183A, is a protein encoded by the TMEM183A gene in humans. As indicated by its name, this protein is localized to cellular membranes, but specific details about its function and biological significance are relatively obscure compared to well-characterized proteins.Transmembrane proteins like TMEM183A typically span the lipid bilayer of cells and can serve various functions, including acting as channels or transporters for molecules, serving as receptors for signaling pathways, or playing a role in the structural integrity of cells and organelles.
The "A" at the end of TMEM183A often denotes that it is one member of a potentially larger family of proteins that share sequence or structural homologies. This family of proteins may have arisen from gene duplications and could have diversified to perform distinct but related functions within the cell.Research on TMEM183A is sparse, and there may be limited information regarding its expression patterns, regulatory mechanisms, and involvement in human physiology or disease states. It's not uncommon for many such transmembrane proteins to be relatively under-studied, awaiting detailed investigation through techniques like gene knockout studies, overexpression assays, and proteomic analyses to elucidate their roles.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation, which is important for the stability and function of many transmembrane proteins. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis, potentially reducing the overall expression of proteins, including TMEM183A. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin is an ionophore that disrupts ion gradients, which can affect transmembrane protein trafficking and expression. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Chlorpromazine can alter cellular membranes and trafficking, potentially impacting the expression of transmembrane proteins. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid regulates gene expression through nuclear receptors and might influence the transcription of TMEM183A. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can alter gene methylation patterns and potentially affect TMEM183A expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that may change chromatin structure and gene expression, potentially influencing TMEM183A. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid, as a histone deacetylase inhibitor, could affect the expression of TMEM183A by altering chromatin accessibility. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Decitabine is a DNA methyltransferase inhibitor that could influence the methylation and expression of the TMEM183A gene. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
Puromycin causes premature termination of protein synthesis, which could non-specifically reduce levels of TMEM183A. | ||||||