TMEM171 Activators
TMEM171 Activators are defined by their ability to indirectly influence the activity, expression, or function of the transmembrane protein 171 through various cellular mechanisms. These activators include a diverse range of compounds that modulate different cellular pathways. Agents such as PMA and forskolin engage with protein kinases like PKC and PKA, respectively, which can phosphorylate proteins and change their activity or cellular localization. This action can alter the function of TMEM171 through post-translational modifications. Similarly, ionomycin, by raising intracellular calcium levels, might affect TMEM171 through calcium-sensitive signaling cascades.
Retinoic acid and 17-beta-Estradiol, by interacting with nuclear hormone receptors, can alter gene expression profiles, which may include TMEM171. Compounds like 5-Azacytidine and trichostatin A affect the expression of genes by epigenetic modifications, potentially leading to an increase in TMEM171 levels. Isoproterenol, acting through adrenergic receptors, and lithium chloride, by inhibiting GSK-3, can lead to changes in cellular signaling pathways that may converge on the modulation of TMEM171. Sodium butyrate, another epigenetic modifier, and DMSO, a solvent known to affect cell membranes, represent additional agents that can modulate the cellular environment and potentially influence the activity and function of TMEM171.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC) which can modulate transmembrane signaling and could influence TMEM171 by altering its phosphorylation state or the membrane environment. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates cAMP levels, which can activate PKA, possibly leading to phosphorylation events that affect TMEM171 localization or function. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Increases intracellular calcium levels, potentially modifying TMEM171 through calcium-sensitive signaling pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene transcription, which could upregulate TMEM171 expression if the TMEM171 gene has retinoic acid-responsive elements. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, which can lead to the demethylation and potential upregulation of TMEM171 if its gene expression is epigenetically regulated. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor, which could upregulate TMEM171 expression through changes in chromatin structure leading to enhanced transcription. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
A beta-adrenergic agonist which can raise intracellular cAMP levels and potentially modulate TMEM171 function through PKA signaling pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3, which can alter signaling pathways and may affect TMEM171 expression or function by modifying the cellular environment. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Engages estrogen receptor signaling, which could impact TMEM171 by influencing gene expression profiles or membrane dynamics. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
A histone deacetylase inhibitor that can cause chromatin remodeling and potentially upregulate TMEM171 expression if the TMEM171 gene is epigenetically regulated. | ||||||