TMEM134 Inhibitors
TMEM134 inhibitors, as a conceptual chemical class, encompass a wide variety of compounds that are not directly associated with TMEM134 but can influence the cellular pathways it may be part of. These chemicals span a diverse set of structures and mechanisms of action. For instance, Rapamycin acts on mTOR signaling, pivotal for cell growth and metabolism. In contrast, Wortmannin and LY294002 target the PI3K pathway, which has vast downstream implications.
The MEK inhibitors, U0126 and PD98059, exert their effect on the MAPK pathway, which is involved in numerous cellular processes from proliferation to differentiation. Similarly, SP600125 and SB203580 target different kinases in the stress and inflammatory pathways. Beyond these, AG-490's focus is on cytokine signaling, while Genistein broadens the scope by inhibiting tyrosine kinases. DAPT's mechanism leans on Notch signaling, with KN-93 modulating calcium-dependent processes and Y-27632 impacting cellular structural elements.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin can inhibit mTOR signaling, a key pathway in cell growth and metabolism. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor which can modulate downstream signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 can inhibit PI3K, influencing various cellular processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, a key kinase in stress-related cellular pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an inhibitor of MEK, impacting MAPK signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK, influencing inflammation and stress responses. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
AG-490 inhibits JAK2, impacting cytokine signaling. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein can inhibit tyrosine kinases, modulating cellular signaling. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
DAPT is a gamma-secretase inhibitor, affecting Notch signaling. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
KN-93 inhibits CaMKII, modulating calcium-dependent cellular processes. | ||||||