The chemical class known as TMCC2 Activators encompasses a diverse range of compounds that are understood to have a modulatory effect on cellular signaling pathways and processes. These activators are characterized by their ability to initiate a cascade of biochemical reactions within the cell that can lead to the activation of TMCC2, a protein embedded within cellular membranes and possibly implicated in various cellular functions. The activation of TMCC2 by these compounds is predicated on their interaction with specific molecular targets that are either directly or indirectly associated with the functional regulation of the TMCC2 protein. The compounds that fall under this category are not uniform in structure or function; rather, they are defined by their shared capacity to influence the activity of TMCC2 through their effects on cellular signaling mechanisms.
These activators include agents that can elevate intracellular secondary messengers, kinase activators, phosphatase inhibitors, ionophores, and calcium modulators, each contributing to intracellular changes that can lead to the activation of TMCC2. The precise mechanisms by which these chemical activators exert their influence on TMCC2 involve modulation of enzymatic activities, alteration of ion gradients, and perturbation of the cellular phosphorylation state. By affecting these fundamental cellular processes, TMCC2 activators can alter the dynamic equilibrium within the cell, leading to the upregulation of TMCC2 activity. The diversity in chemical structure and target specificity of TMCC2 activators reflects the complexity of cellular regulation and underscores the intricate network of signaling pathways that govern protein function. The classification of these chemicals as TMCC2 activators is based on their shared functional impact on cellular pathways that are believed to be relevant to the modulation of TMCC2's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP levels, which can activate PKA and modulate downstream signaling pathways that could activate TMCC2 functions. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Non-specific inhibitor of phosphodiesterases, raises cAMP and cGMP levels, enhancing signaling pathways that could activate TMCC2. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), which may alter phosphorylation states of proteins and could activate TMCC2 activity. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $160.00 $750.00 | 59 | |
Inhibits protein phosphatases PP1 and PP2A, altering the phosphorylation balance and affecting signaling pathways that could activate TMCC2. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Inhibits tyrosine kinases, impacting phosphorylation cascades relevant to TMCC2's role in cellular signaling and could activate TMCC2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, affecting the AKT signaling pathway which may modulate TMCC2 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, affecting pathways that could activate TMCC2's regulatory mechanisms. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Disrupts calcium homeostasis by inhibiting the SERCA pump, affecting calcium signaling pathways linked to TMCC2. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Chelates intracellular calcium, modulating calcium-dependent signaling pathways that could activate TMCC2. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Sodium ionophore that disrupts ion gradients, influencing ion-sensitive signaling pathways and TMCC2 activity. | ||||||