TM4SF18 Activators belong to a specialized class of chemical compounds that interact with the TM4SF18 protein, a member of the transmembrane 4 superfamily. This family is characterized by proteins that span the cellular membrane four times, playing crucial roles in various cellular processes. TM4SF18, in particular, is known for its unique structural features and the specific manner in which it integrates into cellular membranes, influencing the complex interplay of cellular signaling pathways. The activators of TM4SF18 are designed to modulate the function of this protein, thereby affecting the intricate network of signals within the cell. These compounds are synthesized through advanced chemical processes that ensure their specificity and high affinity towards the TM4SF18 protein, making them highly specialized in their action.
The development and study of TM4SF18 Activators involve cutting-edge research in the fields of biochemistry and molecular biology, focusing on the understanding of cellular mechanisms at the molecular level. These activators are the result of extensive research into the structure-function relationship of the TM4SF18 protein, involving sophisticated techniques such as crystallography, molecular docking, and various forms of spectroscopy. Scientists aim to elucidate how these compounds interact with the TM4SF18 protein, altering its conformation and activity. This interaction is pivotal in understanding the role of TM4SF18 within the cell and how its modulation can influence cellular processes. The detailed investigation into the mechanisms of action of TM4SF18 Activators sheds light on the complex web of cellular signaling, contributing significantly to our understanding of cell biology and molecular interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid regulates gene expression through retinoic acid receptors, potentially influencing the expression of TM4SF18. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which may result in the transcriptional regulation of TM4SF18. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
As a DNA methyltransferase inhibitor, it can alter gene expression patterns potentially affecting TM4SF18 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This histone deacetylase inhibitor can change chromatin structure, potentially increasing TM4SF18 transcription. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As a histone deacetylase inhibitor, it may enhance TM4SF18 expression by altering chromatin accessibility. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C which might lead to the induction of TM4SF18 expression through signal transduction pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG may affect gene expression through epigenetic modifications, potentially modulating TM4SF18 expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3, through its active metabolite, can regulate gene expression via the vitamin D receptor, possibly influencing TM4SF18 levels. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
This cAMP analog can mimic the effect of endogenous cAMP and potentially influence TM4SF18 expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences glycogen synthase kinase 3 (GSK-3) activity, which could impact gene expression, including TM4SF18. | ||||||